Antiviral Nanodelivery Systems: Current Trends in Acyclovir Administration

Haniza Hassan, Siti Khadijah Adam, Fauziah Othman, Ahmad Fuad Shamsuddin, Rusliza Basir

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Poor bioavailability of acyclovir in the treatment of viral infections remains one of the major drug delivery concerns of pharmaceutical manufacturers and researchers. Nanoparticulate systems have been exploited with the aim of improving the current pharmacological limitations of acyclovir administration. In fact, nanoparticles do offer many advantages, especially in terms of their physicochemical stability and sustained-release properties. Besides, they are made of biocompatible materials, which are nontoxic to cells. Acyclovir has been a focus since the last decade as one of the low bioavailability drug models loaded in various types of newly synthesized drug delivery vehicles. In this review, compositions and formulations of nanosized acyclovir particles, as well as their stability and pharmacokinetic profile, are discussed in further detail.

Original languageEnglish
Article number4591634
JournalJournal of Nanomaterials
Volume2016
DOIs
Publication statusPublished - 2016

Fingerprint

Acyclovir
Drug delivery
Antiviral Agents
Pharmacokinetics
Biomaterials
Drug products
Nanoparticles
Biocompatible Materials
Chemical analysis
Pharmaceutical Preparations
Biological Availability

ASJC Scopus subject areas

  • Materials Science(all)

Cite this

Hassan, H., Adam, S. K., Othman, F., Shamsuddin, A. F., & Basir, R. (2016). Antiviral Nanodelivery Systems: Current Trends in Acyclovir Administration. Journal of Nanomaterials, 2016, [4591634]. https://doi.org/10.1155/2016/4591634

Antiviral Nanodelivery Systems : Current Trends in Acyclovir Administration. / Hassan, Haniza; Adam, Siti Khadijah; Othman, Fauziah; Shamsuddin, Ahmad Fuad; Basir, Rusliza.

In: Journal of Nanomaterials, Vol. 2016, 4591634, 2016.

Research output: Contribution to journalReview article

Hassan, H, Adam, SK, Othman, F, Shamsuddin, AF & Basir, R 2016, 'Antiviral Nanodelivery Systems: Current Trends in Acyclovir Administration', Journal of Nanomaterials, vol. 2016, 4591634. https://doi.org/10.1155/2016/4591634
Hassan, Haniza ; Adam, Siti Khadijah ; Othman, Fauziah ; Shamsuddin, Ahmad Fuad ; Basir, Rusliza. / Antiviral Nanodelivery Systems : Current Trends in Acyclovir Administration. In: Journal of Nanomaterials. 2016 ; Vol. 2016.
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