Antioxidant and anti-inflammatory activities of Marantodes pumilum (Blume) kuntze and their relationship with the phytochemical content

Shihab Uddin Ahmad, Atiqah Azam, Ahmad Nazrun Shuid, Isa Naina Mohamed

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Marantodes pumilum is a herbaceous plant that has widely recognized for its medicinal use. The plant used widely has led to many studies on its phytochemical identification, pharmacological and toxicological activities. Phytoconstituents found in the Marantodes pumilum extracts showed high antioxidant and anti-inflammatory properties which are essential for many pharmacological effects. The aim of the systematic review is to provide the information of antioxidant and anti-inflammatory properties found in Marantodes pumilum. A critical literature search from three electronic databases such as SCOPUS, EBSCOhost and Ovid Medline was conducted for related studies published from the years 1946 to November 2017. The research studies published in English and related with the antioxidant and anti-inflammatory effects of Marantodes pumilum were the main inclusion criteria in this review. A total 512 relevant articles was identified, whereby 21 articles met the inclusion criteria. Twelve chemical assay studies, five animal studies, two in vitro cell culture study, one combined in vivo animal and chemical study and one combined chemical assay and in vitro cell culture study included in this review. All of the studies reported moderate to noticeable positive effects of Marantodes pumilum against oxidation and inflammation. This systematic review highlights the antioxidant and anti-inflammatory effects and their relation with phytoconstituents of Marantodes pumilum extracts.

Original languageEnglish
Pages (from-to)518-534
Number of pages17
JournalRecords of Natural Products
Volume12
Issue number6
DOIs
Publication statusPublished - 1 Nov 2018

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Phytochemicals
anti-inflammatory activity
phytopharmaceuticals
Anti-Inflammatory Agents
Antioxidants
chemical constituents of plants
antioxidants
systematic review
Cell culture
Assays
Animals
cell culture
Cell Culture Techniques
Pharmacology
extracts
herbaceous plants
assays
Toxicology
electronics
animals

Keywords

  • Anti-inflammatory
  • Antioxidant
  • Marantodes pumilum
  • Phytoconstituents
  • Primulaceae

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Plant Science
  • Organic Chemistry

Cite this

Antioxidant and anti-inflammatory activities of Marantodes pumilum (Blume) kuntze and their relationship with the phytochemical content. / Ahmad, Shihab Uddin; Azam, Atiqah; Shuid, Ahmad Nazrun; Naina Mohamed, Isa.

In: Records of Natural Products, Vol. 12, No. 6, 01.11.2018, p. 518-534.

Research output: Contribution to journalReview article

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