Antimicrobial and cytotoxic properties of some Malaysian traditional vegetables (Ulam)

Muhammad Mukram Mohamed Mackeen, A. M. Ali, S. H. El-Sharkawy, M. Y. Manap, K. M. Salleh, N. H. Lajis, K. Kawazu

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Ethanol extracts of 19 Malaysian traditional vegetables (locally known as 'ulam') belonging to 15 families were screened for antimicrobial and cytotoxic activities. Both the disc diffusion (qualitative) and tube dilution (quantitative) assays were employed for the determination of antimicrobial activity against six pathogenic microorganisms, i.e. two Gram-positive bacterial (Bacillus cereus and Bacillus megaterium), two Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) and two fungi (Aspergillus ochraceous and Cryptococus neoformans). Six extracts, i.e. Anacardium occidentale, Garcinia atroviridis, Averrhoa bilimbi, Polygonum minus, Displazium esculentum and Etlingera elatior, showed antimicrobial with minimum inhibitory concentration (MIC) and minimum lethal concentration (MLC) values in the respective ranges of 100 → 800 μg/ml. The 'ulam' show potential as 'functional food' in view of the significant therapeutic and nutritive benefits.

Original languageEnglish
Pages (from-to)174-178
Number of pages5
JournalInternational Journal of Pharmacognosy
Volume35
Issue number3
Publication statusPublished - 1997
Externally publishedYes

Fingerprint

Garcinia
Anacardium
Polygonum
Bacillus megaterium
Functional Food
Bacillus cereus
Microbial Sensitivity Tests
Aspergillus
Gram-Negative Bacteria
Vegetables
Pseudomonas aeruginosa
Fungi
Ethanol
Escherichia coli
Therapeutics
Averrhoa

Keywords

  • 'ulam'
  • Antimicrobial activity
  • Cytotoxic activity
  • Ethanol extracts
  • Functional Food
  • Malaysian traditional vegetables

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology

Cite this

Mohamed Mackeen, M. M., Ali, A. M., El-Sharkawy, S. H., Manap, M. Y., Salleh, K. M., Lajis, N. H., & Kawazu, K. (1997). Antimicrobial and cytotoxic properties of some Malaysian traditional vegetables (Ulam). International Journal of Pharmacognosy, 35(3), 174-178.

Antimicrobial and cytotoxic properties of some Malaysian traditional vegetables (Ulam). / Mohamed Mackeen, Muhammad Mukram; Ali, A. M.; El-Sharkawy, S. H.; Manap, M. Y.; Salleh, K. M.; Lajis, N. H.; Kawazu, K.

In: International Journal of Pharmacognosy, Vol. 35, No. 3, 1997, p. 174-178.

Research output: Contribution to journalArticle

Mohamed Mackeen, MM, Ali, AM, El-Sharkawy, SH, Manap, MY, Salleh, KM, Lajis, NH & Kawazu, K 1997, 'Antimicrobial and cytotoxic properties of some Malaysian traditional vegetables (Ulam)', International Journal of Pharmacognosy, vol. 35, no. 3, pp. 174-178.
Mohamed Mackeen, Muhammad Mukram ; Ali, A. M. ; El-Sharkawy, S. H. ; Manap, M. Y. ; Salleh, K. M. ; Lajis, N. H. ; Kawazu, K. / Antimicrobial and cytotoxic properties of some Malaysian traditional vegetables (Ulam). In: International Journal of Pharmacognosy. 1997 ; Vol. 35, No. 3. pp. 174-178.
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