Antibody deficiency with hyper IgM--a case report.

Lokman Mohd. Noh, S. M. Low, I. Lajin, Norlia Abdullah

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 20-month-old Indian boy presented with recurrent pyogenic infections and failure to thrive. His IgG and IgA levels were low, but his IgM was elevated. He also had undetectable isohaemagglutinin titre and neutropenia, both parameters being poor prognostic indicators in this very rare primary immunodeficiency state--antibody deficiency with hyper IgM. Our patient subsequently succumbed to Pseudomonas aeruginosa septicaemia and meningitis inspite of aggressive antibiotic and intravenous gammaglobulin therapy. To the best of our knowledge, this is the first such case to be documented in Malaysia.

Original languageEnglish
Pages (from-to)121-123
Number of pages3
JournalThe Malaysian journal of pathology
Volume14
Issue number2
Publication statusPublished - Dec 1992

Fingerprint

Immunoglobulin M
Failure to Thrive
Antibodies
Malaysia
Hemagglutinins
Neutropenia
Meningitis
Pseudomonas aeruginosa
Immunoglobulin A
Sepsis
Immunoglobulin G
Anti-Bacterial Agents
Infection
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Antibody deficiency with hyper IgM--a case report. / Mohd. Noh, Lokman; Low, S. M.; Lajin, I.; Abdullah, Norlia.

In: The Malaysian journal of pathology, Vol. 14, No. 2, 12.1992, p. 121-123.

Research output: Contribution to journalArticle

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