Antibacterial, antioxidant and cytotoxicity properties of traditionally used Melastoma malabathricum linn leaves

Mourouge Saadi Abbas Alwash, Nazlina Ibrahim, Wan Yaacob Wan Ahmad, Laily Bin Din

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The study is aimed to evaluate the antibacterial, antioxidant and cytotoxicity properties of the Methanol extract of Melastoma malabathricum (MMML). The antibacterial of the Methanol extract of M. malabathricum leaves (MMML) was assessed against Gram-positive and Gram-negative bacteria by disk diffusion method, minimum inhibitory concentration and direct-TLC bioautography. In addition, the antioxidant activity was detected by DPPH radical scavenging activity and cytotoxicity property was determined by MTT assay. The data obtained from disk diffusion method and (MICs) values showed that the MMML possesses antibacterial activity against Gram-positive and Gram-negative bacteria with various values. In addition, direct TLC-bioautography revealed the presence of antibacterial components. The MMML exhibited higher antioxidant activity equal to standard antioxidant ascorbic acid accompanied with low cytotoxicity. Therefore, the MMML has potent antibacterial and antioxidant activities that are strongly associated with its ethno medicinal values.

Original languageEnglish
Pages (from-to)6-12
Number of pages7
JournalAdvance Journal of Food Science and Technology
Volume6
Issue number1
Publication statusPublished - 2014

Fingerprint

Melastoma malabathricum
Cytotoxicity
Antioxidants
cytotoxicity
antioxidants
antioxidant activity
leaves
Gram-Negative Bacteria
Gram-negative bacteria
Methanol
Bacteria
methanol
Ascorbic acid
Scavenging
extracts
Microbial Sensitivity Tests
minimum inhibitory concentration
Ascorbic Acid
Assays
ascorbic acid

Keywords

  • Antibacterial activity
  • Antioxidant activity
  • Cytotoxicity properity
  • Melastoma malabathricum

ASJC Scopus subject areas

  • Food Science
  • Industrial and Manufacturing Engineering
  • Chemistry(all)

Cite this

Antibacterial, antioxidant and cytotoxicity properties of traditionally used Melastoma malabathricum linn leaves. / Alwash, Mourouge Saadi Abbas; Ibrahim, Nazlina; Wan Ahmad, Wan Yaacob; Din, Laily Bin.

In: Advance Journal of Food Science and Technology, Vol. 6, No. 1, 2014, p. 6-12.

Research output: Contribution to journalArticle

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