Antibacterial activity of alkaloid extracts from ochrosia oppositifolia

Puteri I.A.M. Mahmud, Wan Yaacob Wan Ahmad, Nazlina Ibrahim

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Ochrosia oppositifolia can be found along the coastline and is locally known as ‘Mempelam pasih’ or ‘Mangga laut’. In this study, the alkaloids from the leaves, stem-bark and roots were extracted and tested for their antibacterial activity. So far, no previous studies have been carried out to determine the antibacterial potential of the extracts. Each extract was tested using disc-diffusion and minimum inhibitory concentration (MIC) methods. The highest inhibitory diameters shown by 10 mg/mL extracts of the leaves and stem-bark against Staphylococcus aureus and the roots against MRSA were 10.0±2.8 and 10.5±2.1 and 14.0±2.8 mm. On the other hand, the MIC values exhibited by the leaf and stem-bark extracts against Bacillus subtilis, Salmonella thyphimurium and Serratia marcescens and the root extract against Vibrio fluvialis were 3.75 and 0.94 and 0.12 mg/mL. This study broadens the bioactivity potential of the plant and the information obtained can be utilized for pharmacological purposes.

Original languageEnglish
Pages (from-to)1279-1284
Number of pages6
JournalSains Malaysiana
Volume46
Issue number8
DOIs
Publication statusPublished - 1 Aug 2017

Fingerprint

Ochrosia
alkaloids
bark
extracts
minimum inhibitory concentration
stems
Vibrio fluvialis
Serratia marcescens
leaf extracts
Bacillus subtilis
leaves
Staphylococcus aureus
Salmonella
coasts

Keywords

  • Alkaloid extract
  • Antibacterial activity
  • Disc diffusion
  • Minimum inhibitory concentration
  • Ochrosia oppositifolia

ASJC Scopus subject areas

  • General

Cite this

Antibacterial activity of alkaloid extracts from ochrosia oppositifolia. / Mahmud, Puteri I.A.M.; Wan Ahmad, Wan Yaacob; Ibrahim, Nazlina.

In: Sains Malaysiana, Vol. 46, No. 8, 01.08.2017, p. 1279-1284.

Research output: Contribution to journalArticle

Mahmud, Puteri I.A.M. ; Wan Ahmad, Wan Yaacob ; Ibrahim, Nazlina. / Antibacterial activity of alkaloid extracts from ochrosia oppositifolia. In: Sains Malaysiana. 2017 ; Vol. 46, No. 8. pp. 1279-1284.
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