Anterior segment characteristics of keratoconus eyes in a sample of Asian population

Fereshteh Abolbashari, Norhani Mohidin, Seyed Mahdi Ahmadi Hosseini, Bariah Mohd. Ali, Shamala Retnasabapathy

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Purpose: To assess changes in anterior segment parameters of keratoconus eyes at different stages of the disease in a sample of the Asian population. Methods: Files of 32 patients (48 eyes) diagnosed as clinical keratoconus were assessed and the following parameters noted: central corneal thickness (CCT), thinnest corneal thickness (TCT), location of thinnest pachymetry, anterior chamber depth (ACD) at the centre from posterior corneal surface, ACD at 1, 2 and 3. mm inferior-paracentral, ACD at thinnest pachymetry, anterior chamber volume (ACV) and anterior chamber angle (ACA). For analysis, keratoconus eyes were classified into 3 subgroups according to mean keratometry readings (mild: K≤. 47.0. D, moderate: 47.0. <. K<. 52.0. D, and severe: K≥. 52.0. D). Forty-five subjects (45 right eyes) were recruited as a control group. They underwent Pentacam tomographic evaluation. The same parameters were recorded for control subjects as in the keratoconus patients. Results: Each keratoconus subgroup comprised of 16 eyes. CCT, TCT, ACD at centre, ACD at 1, 2. mm inferior-paracentral and ACD at thinnest pachymetry were statistically different between mild and severe keratoconus groups (P<. 0.05). There were also significant differences between normal with each of the moderate and severe keratoconus groups (P<. 0.05). Non-significant differences were found in ACV (P=0.84) and ACA (P=0.71) between all measured groups. Conclusion: With the exception of ACV and ACA, parameters that include CCT, TCT, ACD at centre, thinnest pachymetry and 1, 2. mm inferior-paracentral were significantly altered with progression of keratoconus. These findings may be useful in monitoring and management of keratoconus patients.

Original languageEnglish
Pages (from-to)191-195
Number of pages5
JournalContact Lens and Anterior Eye
Volume36
Issue number4
DOIs
Publication statusPublished - Aug 2013

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Keratoconus
Anterior Chamber
Population
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Keywords

  • Anterior chamber
  • Asian
  • Keratoconus
  • Pentacam

ASJC Scopus subject areas

  • Ophthalmology
  • Optometry

Cite this

Anterior segment characteristics of keratoconus eyes in a sample of Asian population. / Abolbashari, Fereshteh; Mohidin, Norhani; Ahmadi Hosseini, Seyed Mahdi; Mohd. Ali, Bariah; Retnasabapathy, Shamala.

In: Contact Lens and Anterior Eye, Vol. 36, No. 4, 08.2013, p. 191-195.

Research output: Contribution to journalArticle

Abolbashari, Fereshteh ; Mohidin, Norhani ; Ahmadi Hosseini, Seyed Mahdi ; Mohd. Ali, Bariah ; Retnasabapathy, Shamala. / Anterior segment characteristics of keratoconus eyes in a sample of Asian population. In: Contact Lens and Anterior Eye. 2013 ; Vol. 36, No. 4. pp. 191-195.
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abstract = "Purpose: To assess changes in anterior segment parameters of keratoconus eyes at different stages of the disease in a sample of the Asian population. Methods: Files of 32 patients (48 eyes) diagnosed as clinical keratoconus were assessed and the following parameters noted: central corneal thickness (CCT), thinnest corneal thickness (TCT), location of thinnest pachymetry, anterior chamber depth (ACD) at the centre from posterior corneal surface, ACD at 1, 2 and 3. mm inferior-paracentral, ACD at thinnest pachymetry, anterior chamber volume (ACV) and anterior chamber angle (ACA). For analysis, keratoconus eyes were classified into 3 subgroups according to mean keratometry readings (mild: K≤. 47.0. D, moderate: 47.0. <. K<. 52.0. D, and severe: K≥. 52.0. D). Forty-five subjects (45 right eyes) were recruited as a control group. They underwent Pentacam tomographic evaluation. The same parameters were recorded for control subjects as in the keratoconus patients. Results: Each keratoconus subgroup comprised of 16 eyes. CCT, TCT, ACD at centre, ACD at 1, 2. mm inferior-paracentral and ACD at thinnest pachymetry were statistically different between mild and severe keratoconus groups (P<. 0.05). There were also significant differences between normal with each of the moderate and severe keratoconus groups (P<. 0.05). Non-significant differences were found in ACV (P=0.84) and ACA (P=0.71) between all measured groups. Conclusion: With the exception of ACV and ACA, parameters that include CCT, TCT, ACD at centre, thinnest pachymetry and 1, 2. mm inferior-paracentral were significantly altered with progression of keratoconus. These findings may be useful in monitoring and management of keratoconus patients.",
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AU - Retnasabapathy, Shamala

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N2 - Purpose: To assess changes in anterior segment parameters of keratoconus eyes at different stages of the disease in a sample of the Asian population. Methods: Files of 32 patients (48 eyes) diagnosed as clinical keratoconus were assessed and the following parameters noted: central corneal thickness (CCT), thinnest corneal thickness (TCT), location of thinnest pachymetry, anterior chamber depth (ACD) at the centre from posterior corneal surface, ACD at 1, 2 and 3. mm inferior-paracentral, ACD at thinnest pachymetry, anterior chamber volume (ACV) and anterior chamber angle (ACA). For analysis, keratoconus eyes were classified into 3 subgroups according to mean keratometry readings (mild: K≤. 47.0. D, moderate: 47.0. <. K<. 52.0. D, and severe: K≥. 52.0. D). Forty-five subjects (45 right eyes) were recruited as a control group. They underwent Pentacam tomographic evaluation. The same parameters were recorded for control subjects as in the keratoconus patients. Results: Each keratoconus subgroup comprised of 16 eyes. CCT, TCT, ACD at centre, ACD at 1, 2. mm inferior-paracentral and ACD at thinnest pachymetry were statistically different between mild and severe keratoconus groups (P<. 0.05). There were also significant differences between normal with each of the moderate and severe keratoconus groups (P<. 0.05). Non-significant differences were found in ACV (P=0.84) and ACA (P=0.71) between all measured groups. Conclusion: With the exception of ACV and ACA, parameters that include CCT, TCT, ACD at centre, thinnest pachymetry and 1, 2. mm inferior-paracentral were significantly altered with progression of keratoconus. These findings may be useful in monitoring and management of keratoconus patients.

AB - Purpose: To assess changes in anterior segment parameters of keratoconus eyes at different stages of the disease in a sample of the Asian population. Methods: Files of 32 patients (48 eyes) diagnosed as clinical keratoconus were assessed and the following parameters noted: central corneal thickness (CCT), thinnest corneal thickness (TCT), location of thinnest pachymetry, anterior chamber depth (ACD) at the centre from posterior corneal surface, ACD at 1, 2 and 3. mm inferior-paracentral, ACD at thinnest pachymetry, anterior chamber volume (ACV) and anterior chamber angle (ACA). For analysis, keratoconus eyes were classified into 3 subgroups according to mean keratometry readings (mild: K≤. 47.0. D, moderate: 47.0. <. K<. 52.0. D, and severe: K≥. 52.0. D). Forty-five subjects (45 right eyes) were recruited as a control group. They underwent Pentacam tomographic evaluation. The same parameters were recorded for control subjects as in the keratoconus patients. Results: Each keratoconus subgroup comprised of 16 eyes. CCT, TCT, ACD at centre, ACD at 1, 2. mm inferior-paracentral and ACD at thinnest pachymetry were statistically different between mild and severe keratoconus groups (P<. 0.05). There were also significant differences between normal with each of the moderate and severe keratoconus groups (P<. 0.05). Non-significant differences were found in ACV (P=0.84) and ACA (P=0.71) between all measured groups. Conclusion: With the exception of ACV and ACA, parameters that include CCT, TCT, ACD at centre, thinnest pachymetry and 1, 2. mm inferior-paracentral were significantly altered with progression of keratoconus. These findings may be useful in monitoring and management of keratoconus patients.

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