Annonaceae: Breaking the wall of inflammation

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Inventories of tropical forests have listed Annonaceae as one of the most diverse plant families. For centuries, it is employed in traditional medicines to cure various pathological conditions including snakebite, analgesic, astringent, diarrhea, dysentery, arthritis pain, rheumatism, neuralgia, and weight loss etc. Phytochemical analysis of Annonaceae family have reported the occurrence of alkaloids, flavonoids, triterpenes, diterpenes and diterpene flavone glycosides, sterols, lignans, and annonaceous acetogenin characteristically affiliated with Annonaceae sp. Numerous past studies have underlined the pleotropic pharmacological activities of the crude extracts and isolated compounds from Annonaceae species. This review is an effort to abridge the ethnobotany, morphology, phytochemistry, toxicity, and particularly focusing on the anti-inflammatory activity of the Annonaceae species.

Original languageEnglish
Article number752
JournalFrontiers in Pharmacology
Volume8
Issue numberOCT
DOIs
Publication statusPublished - 20 Oct 2017

Fingerprint

Annonaceae
Inflammation
flavone
Diterpenes
Ethnobotany
Acetogenins
Astringents
Snake Bites
Lignans
Dysentery
Triterpenes
Phytochemicals
Traditional Medicine
Neuralgia
Sterols
Glycosides
Rheumatic Diseases
Complex Mixtures
Alkaloids
Flavonoids

Keywords

  • Annonaceae
  • Anti-inflammatory
  • Cycloxegenase
  • Cytokines
  • Nuclear factor kappaB
  • Prostaglandins
  • Reactive oxygen species

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

Cite this

Annonaceae : Breaking the wall of inflammation. / Attiq, Ali; Jalil, Juriyati; Husain, Khairana.

In: Frontiers in Pharmacology, Vol. 8, No. OCT, 752, 20.10.2017.

Research output: Contribution to journalReview article

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