An investigation of errors

The preparation and administration of parenteral medications in an intensive care unit of a tertiary teaching hospital in Malaysia

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: This study was carried out to investigate the incidence, types, and factors associated with parenteral medication preparation/administration errors. The study also investigates the concentration accuracy of prepared drug infusions and the adherence to good practices by the nurses. Methods: This was a prospective study conducted in a general intensive care unit (GICU) of a tertiary teaching hospital in Malaysia, using an observation method. The preparation and administration of the parenteral medications by the nurses were observed, and the details were recorded using a standard checklist. The drug infusions (noradrenaline) prepared by the nurses were collected for a concentration analysis using a high-performance liquid chromatography (HPLC). Results: This study found that 79% of the parenteral medications prepared and administered had one or more error. There were 33% doses with 2 or more errors while 6% doses contained 3 errors. The most common errors involved incorrect drug preparation (57%), followed by incorrect administration rate (33%). There was no double-checking performed in the preparation/administration of all (100%) parenteral doses. In terms of concentration accuracy, 48% of the prepared drug infusions contained errors. Failure to label syringe properly was found to result in more errors per dose (P

Original languageEnglish
Pages (from-to)325-329
Number of pages5
JournalInternational Journal of Pharmacy and Pharmaceutical Sciences
Volume8
Issue number3
Publication statusPublished - 2016

Fingerprint

Malaysia
Tertiary Care Centers
Teaching Hospitals
Intensive Care Units
Nurses
Pharmaceutical Preparations
Drug Compounding
Syringes
Checklist
Norepinephrine
High Pressure Liquid Chromatography
Observation
Prospective Studies
Incidence

Keywords

  • Intensive care unit
  • Medication error
  • Nurses
  • Observation
  • Parenteral medication

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Pharmacology

Cite this

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abstract = "Objective: This study was carried out to investigate the incidence, types, and factors associated with parenteral medication preparation/administration errors. The study also investigates the concentration accuracy of prepared drug infusions and the adherence to good practices by the nurses. Methods: This was a prospective study conducted in a general intensive care unit (GICU) of a tertiary teaching hospital in Malaysia, using an observation method. The preparation and administration of the parenteral medications by the nurses were observed, and the details were recorded using a standard checklist. The drug infusions (noradrenaline) prepared by the nurses were collected for a concentration analysis using a high-performance liquid chromatography (HPLC). Results: This study found that 79{\%} of the parenteral medications prepared and administered had one or more error. There were 33{\%} doses with 2 or more errors while 6{\%} doses contained 3 errors. The most common errors involved incorrect drug preparation (57{\%}), followed by incorrect administration rate (33{\%}). There was no double-checking performed in the preparation/administration of all (100{\%}) parenteral doses. In terms of concentration accuracy, 48{\%} of the prepared drug infusions contained errors. Failure to label syringe properly was found to result in more errors per dose (P",
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journal = "International Journal of Pharmacy and Pharmaceutical Sciences",
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AU - Mohd Said, Mazlina

AU - Abdul Rahman, Raha

AU - Taha, Nur Akmar

PY - 2016

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AB - Objective: This study was carried out to investigate the incidence, types, and factors associated with parenteral medication preparation/administration errors. The study also investigates the concentration accuracy of prepared drug infusions and the adherence to good practices by the nurses. Methods: This was a prospective study conducted in a general intensive care unit (GICU) of a tertiary teaching hospital in Malaysia, using an observation method. The preparation and administration of the parenteral medications by the nurses were observed, and the details were recorded using a standard checklist. The drug infusions (noradrenaline) prepared by the nurses were collected for a concentration analysis using a high-performance liquid chromatography (HPLC). Results: This study found that 79% of the parenteral medications prepared and administered had one or more error. There were 33% doses with 2 or more errors while 6% doses contained 3 errors. The most common errors involved incorrect drug preparation (57%), followed by incorrect administration rate (33%). There was no double-checking performed in the preparation/administration of all (100%) parenteral doses. In terms of concentration accuracy, 48% of the prepared drug infusions contained errors. Failure to label syringe properly was found to result in more errors per dose (P

KW - Intensive care unit

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KW - Nurses

KW - Observation

KW - Parenteral medication

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