An epidemiological study of septic arthritis in Kuala Lumpur Hospital

M. Razak, J. Nasiruddin

    Research output: Contribution to journalArticle

    7 Citations (Scopus)

    Abstract

    Forty-one patients with 42 joint infections were admitted to the hospital between June 1989 and June 1994. An overview on the behaviour of septic arthritis in both children and adults, at presentation and after various types of treatment was done. There were 32 knees, 7 hips, 2 elbows and 1 shoulder. Duration of symptoms, type of organism, type of joint damage, presence of preexisting joint problems and presence of osteomyelitis are among the important factors with prognostic significance. Seventy three percent of patients with less than 7 days duration of symptoms had satisfactory results. Whereas when of the duration of symptoms exceeded 7 days, 75% of the patients bad unsatisfactory outcome. All cases with poor outcome had positive cultures. Staphylococcus aureus was responsible for 77% of the culture-positive cases. All Staphylococcus aureus in this study were penicillin-resistant but sensitive to cloxacillin. There were 3 instances were Staphylococcus became resistant to cloxacillin following recurrence of septic arthritis. However, they were still sensitive to third generation cephalosporin. Staphylococcus aureus was capable of producing poor results even when the case was treated early. Other organisms were gram-negative bacilli which infect patients with suppressed immune system, that is, intravenous drug abuser, systemic steroid therapy and diabetes mellitus. Open arthrotomy was the method of drainage used in all his sepsis. This method was also the most reliable method of joint drainage in other joints compared to aspiration method when frank pus was already present. Most immuno-compromised patients recovered badly from septic arthritis. Associated adjacent osteomyelitis, preexisting chronic arthritis and recent intra-articular fractures were also noted to adversely affect the functional outcome.

    Original languageEnglish
    Pages (from-to)86-94
    Number of pages9
    JournalMedical Journal of Malaysia
    Volume53
    Issue numberSUPPL. A
    Publication statusPublished - 1998

    Fingerprint

    Infectious Arthritis
    Epidemiologic Studies
    Joints
    Cloxacillin
    Staphylococcus aureus
    Osteomyelitis
    Drainage
    Intra-Articular Fractures
    Suppuration
    Cephalosporins
    Elbow
    Drug Users
    Staphylococcus
    Penicillins
    Bacillus
    Arthritis
    Hip
    Immune System
    Knee
    Sepsis

    ASJC Scopus subject areas

    • Medicine(all)

    Cite this

    An epidemiological study of septic arthritis in Kuala Lumpur Hospital. / Razak, M.; Nasiruddin, J.

    In: Medical Journal of Malaysia, Vol. 53, No. SUPPL. A, 1998, p. 86-94.

    Research output: Contribution to journalArticle

    Razak, M & Nasiruddin, J 1998, 'An epidemiological study of septic arthritis in Kuala Lumpur Hospital', Medical Journal of Malaysia, vol. 53, no. SUPPL. A, pp. 86-94.
    Razak, M. ; Nasiruddin, J. / An epidemiological study of septic arthritis in Kuala Lumpur Hospital. In: Medical Journal of Malaysia. 1998 ; Vol. 53, No. SUPPL. A. pp. 86-94.
    @article{2b7d4755d6874fc1920faae026546f00,
    title = "An epidemiological study of septic arthritis in Kuala Lumpur Hospital",
    abstract = "Forty-one patients with 42 joint infections were admitted to the hospital between June 1989 and June 1994. An overview on the behaviour of septic arthritis in both children and adults, at presentation and after various types of treatment was done. There were 32 knees, 7 hips, 2 elbows and 1 shoulder. Duration of symptoms, type of organism, type of joint damage, presence of preexisting joint problems and presence of osteomyelitis are among the important factors with prognostic significance. Seventy three percent of patients with less than 7 days duration of symptoms had satisfactory results. Whereas when of the duration of symptoms exceeded 7 days, 75{\%} of the patients bad unsatisfactory outcome. All cases with poor outcome had positive cultures. Staphylococcus aureus was responsible for 77{\%} of the culture-positive cases. All Staphylococcus aureus in this study were penicillin-resistant but sensitive to cloxacillin. There were 3 instances were Staphylococcus became resistant to cloxacillin following recurrence of septic arthritis. However, they were still sensitive to third generation cephalosporin. Staphylococcus aureus was capable of producing poor results even when the case was treated early. Other organisms were gram-negative bacilli which infect patients with suppressed immune system, that is, intravenous drug abuser, systemic steroid therapy and diabetes mellitus. Open arthrotomy was the method of drainage used in all his sepsis. This method was also the most reliable method of joint drainage in other joints compared to aspiration method when frank pus was already present. Most immuno-compromised patients recovered badly from septic arthritis. Associated adjacent osteomyelitis, preexisting chronic arthritis and recent intra-articular fractures were also noted to adversely affect the functional outcome.",
    author = "M. Razak and J. Nasiruddin",
    year = "1998",
    language = "English",
    volume = "53",
    pages = "86--94",
    journal = "Medical Journal of Malaysia",
    issn = "0300-5283",
    publisher = "Malaysian Medical Association",
    number = "SUPPL. A",

    }

    TY - JOUR

    T1 - An epidemiological study of septic arthritis in Kuala Lumpur Hospital

    AU - Razak, M.

    AU - Nasiruddin, J.

    PY - 1998

    Y1 - 1998

    N2 - Forty-one patients with 42 joint infections were admitted to the hospital between June 1989 and June 1994. An overview on the behaviour of septic arthritis in both children and adults, at presentation and after various types of treatment was done. There were 32 knees, 7 hips, 2 elbows and 1 shoulder. Duration of symptoms, type of organism, type of joint damage, presence of preexisting joint problems and presence of osteomyelitis are among the important factors with prognostic significance. Seventy three percent of patients with less than 7 days duration of symptoms had satisfactory results. Whereas when of the duration of symptoms exceeded 7 days, 75% of the patients bad unsatisfactory outcome. All cases with poor outcome had positive cultures. Staphylococcus aureus was responsible for 77% of the culture-positive cases. All Staphylococcus aureus in this study were penicillin-resistant but sensitive to cloxacillin. There were 3 instances were Staphylococcus became resistant to cloxacillin following recurrence of septic arthritis. However, they were still sensitive to third generation cephalosporin. Staphylococcus aureus was capable of producing poor results even when the case was treated early. Other organisms were gram-negative bacilli which infect patients with suppressed immune system, that is, intravenous drug abuser, systemic steroid therapy and diabetes mellitus. Open arthrotomy was the method of drainage used in all his sepsis. This method was also the most reliable method of joint drainage in other joints compared to aspiration method when frank pus was already present. Most immuno-compromised patients recovered badly from septic arthritis. Associated adjacent osteomyelitis, preexisting chronic arthritis and recent intra-articular fractures were also noted to adversely affect the functional outcome.

    AB - Forty-one patients with 42 joint infections were admitted to the hospital between June 1989 and June 1994. An overview on the behaviour of septic arthritis in both children and adults, at presentation and after various types of treatment was done. There were 32 knees, 7 hips, 2 elbows and 1 shoulder. Duration of symptoms, type of organism, type of joint damage, presence of preexisting joint problems and presence of osteomyelitis are among the important factors with prognostic significance. Seventy three percent of patients with less than 7 days duration of symptoms had satisfactory results. Whereas when of the duration of symptoms exceeded 7 days, 75% of the patients bad unsatisfactory outcome. All cases with poor outcome had positive cultures. Staphylococcus aureus was responsible for 77% of the culture-positive cases. All Staphylococcus aureus in this study were penicillin-resistant but sensitive to cloxacillin. There were 3 instances were Staphylococcus became resistant to cloxacillin following recurrence of septic arthritis. However, they were still sensitive to third generation cephalosporin. Staphylococcus aureus was capable of producing poor results even when the case was treated early. Other organisms were gram-negative bacilli which infect patients with suppressed immune system, that is, intravenous drug abuser, systemic steroid therapy and diabetes mellitus. Open arthrotomy was the method of drainage used in all his sepsis. This method was also the most reliable method of joint drainage in other joints compared to aspiration method when frank pus was already present. Most immuno-compromised patients recovered badly from septic arthritis. Associated adjacent osteomyelitis, preexisting chronic arthritis and recent intra-articular fractures were also noted to adversely affect the functional outcome.

    UR - http://www.scopus.com/inward/record.url?scp=0032411125&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0032411125&partnerID=8YFLogxK

    M3 - Article

    VL - 53

    SP - 86

    EP - 94

    JO - Medical Journal of Malaysia

    JF - Medical Journal of Malaysia

    SN - 0300-5283

    IS - SUPPL. A

    ER -