An automated liver tumour segmentation from abdominal CT scans for hepatic surgical planning

Omar Ibrahim Alirr, Ashrani Aizzuddin Abd Rahni, Ehsan Golkar

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: Segmentation of liver tumours is an important part of the 3D visualisation of the liver anatomy for surgical planning. The spatial relationship between tumours and other structures inside the liver forms the basis of preoperative surgical risk assessment. However, the automatic segmentation of liver tumours from abdominal CT scans is riddled with challenges. Tumours located at the border of the liver impose a big challenge as the surrounding tissues could have similar intensities. Methods: In this work, we introduce a fully automated liver tumour segmentation approach in contrast-enhanced CT datasets. The method is a multi-stage technique which starts with contrast enhancement of the tumours using anisotropic filtering, followed by adaptive thresholding to extract the initial mask of the tumours from an identified liver region of interest. Localised level set-based active contours are used to extend the mask to the tumour boundaries. Results: The proposed method is validated on the IRCAD database with pathologies that offer highly variable and complex liver tumours. The results are compared quantitatively to the ground truth, which is delineated by experts. We achieved an average dice similarity coefficient of 75% over all patients with liver tumours in the database with overall absolute relative volume difference of 11%. This is comparable to other recent works, which include semiautomated methods, although they were validated on different datasets. Conclusions: The proposed approach aims to segment tumours inside the liver envelope automatically with a level of accuracy adequate for its use as a tool for surgical planning using abdominal CT images. The approach will be validated on larger datasets in the future.

Original languageEnglish
Pages (from-to)1-8
Number of pages8
JournalInternational journal of computer assisted radiology and surgery
DOIs
Publication statusAccepted/In press - 2 Jun 2018

Fingerprint

Computerized tomography
Liver
Tumors
Planning
Neoplasms
Masks
Databases
Pathology
Risk assessment
Anatomy
Visualization
Tissue

Keywords

  • Abdominal CT
  • Automatic segmentation
  • Liver tumour
  • Surgical planning

ASJC Scopus subject areas

  • Surgery
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging
  • Computer Vision and Pattern Recognition
  • Health Informatics
  • Computer Science Applications
  • Computer Graphics and Computer-Aided Design

Cite this

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title = "An automated liver tumour segmentation from abdominal CT scans for hepatic surgical planning",
abstract = "Purpose: Segmentation of liver tumours is an important part of the 3D visualisation of the liver anatomy for surgical planning. The spatial relationship between tumours and other structures inside the liver forms the basis of preoperative surgical risk assessment. However, the automatic segmentation of liver tumours from abdominal CT scans is riddled with challenges. Tumours located at the border of the liver impose a big challenge as the surrounding tissues could have similar intensities. Methods: In this work, we introduce a fully automated liver tumour segmentation approach in contrast-enhanced CT datasets. The method is a multi-stage technique which starts with contrast enhancement of the tumours using anisotropic filtering, followed by adaptive thresholding to extract the initial mask of the tumours from an identified liver region of interest. Localised level set-based active contours are used to extend the mask to the tumour boundaries. Results: The proposed method is validated on the IRCAD database with pathologies that offer highly variable and complex liver tumours. The results are compared quantitatively to the ground truth, which is delineated by experts. We achieved an average dice similarity coefficient of 75{\%} over all patients with liver tumours in the database with overall absolute relative volume difference of 11{\%}. This is comparable to other recent works, which include semiautomated methods, although they were validated on different datasets. Conclusions: The proposed approach aims to segment tumours inside the liver envelope automatically with a level of accuracy adequate for its use as a tool for surgical planning using abdominal CT images. The approach will be validated on larger datasets in the future.",
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AU - Abd Rahni, Ashrani Aizzuddin

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N2 - Purpose: Segmentation of liver tumours is an important part of the 3D visualisation of the liver anatomy for surgical planning. The spatial relationship between tumours and other structures inside the liver forms the basis of preoperative surgical risk assessment. However, the automatic segmentation of liver tumours from abdominal CT scans is riddled with challenges. Tumours located at the border of the liver impose a big challenge as the surrounding tissues could have similar intensities. Methods: In this work, we introduce a fully automated liver tumour segmentation approach in contrast-enhanced CT datasets. The method is a multi-stage technique which starts with contrast enhancement of the tumours using anisotropic filtering, followed by adaptive thresholding to extract the initial mask of the tumours from an identified liver region of interest. Localised level set-based active contours are used to extend the mask to the tumour boundaries. Results: The proposed method is validated on the IRCAD database with pathologies that offer highly variable and complex liver tumours. The results are compared quantitatively to the ground truth, which is delineated by experts. We achieved an average dice similarity coefficient of 75% over all patients with liver tumours in the database with overall absolute relative volume difference of 11%. This is comparable to other recent works, which include semiautomated methods, although they were validated on different datasets. Conclusions: The proposed approach aims to segment tumours inside the liver envelope automatically with a level of accuracy adequate for its use as a tool for surgical planning using abdominal CT images. The approach will be validated on larger datasets in the future.

AB - Purpose: Segmentation of liver tumours is an important part of the 3D visualisation of the liver anatomy for surgical planning. The spatial relationship between tumours and other structures inside the liver forms the basis of preoperative surgical risk assessment. However, the automatic segmentation of liver tumours from abdominal CT scans is riddled with challenges. Tumours located at the border of the liver impose a big challenge as the surrounding tissues could have similar intensities. Methods: In this work, we introduce a fully automated liver tumour segmentation approach in contrast-enhanced CT datasets. The method is a multi-stage technique which starts with contrast enhancement of the tumours using anisotropic filtering, followed by adaptive thresholding to extract the initial mask of the tumours from an identified liver region of interest. Localised level set-based active contours are used to extend the mask to the tumour boundaries. Results: The proposed method is validated on the IRCAD database with pathologies that offer highly variable and complex liver tumours. The results are compared quantitatively to the ground truth, which is delineated by experts. We achieved an average dice similarity coefficient of 75% over all patients with liver tumours in the database with overall absolute relative volume difference of 11%. This is comparable to other recent works, which include semiautomated methods, although they were validated on different datasets. Conclusions: The proposed approach aims to segment tumours inside the liver envelope automatically with a level of accuracy adequate for its use as a tool for surgical planning using abdominal CT images. The approach will be validated on larger datasets in the future.

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