An audit of reported acute transfusion reactions in Universiti Kebangsaan Malaysia Medical Centre

Y. Rabeya, A. H. Abdul-Kahar, Leong Chooi Fun

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Transfusion is an irreversible event which carries potential benefi ts as well as risk to the recipient. The objective of this study was to analyse all reported transfusion reactions of the year 2008 in the Blood Bank Unit of Universiti Kebangsaan Malaysia Medical Centre (UKMMC). This is a retrospective study that was carried out by retrieving data from the laboratory information system. A total of 27842 transfusions were documented and the total reported transfusion reactions were 149. The incidence of transfusion reaction was 1 in 187 of all transfusions (0.54%); in which 69 (0.25%) were allergic in nature and 61 (0.22%) were febrile non-haemolytic transfusion reactions (FNHTR). Hypotensive reactions were identifi ed in 6 (0.02%) patients. There were 9 (0.03%) cases reported with haemoglobinuria where no serological evidence of haemolytic transfusion reaction (HTR) was found. One HTR (0.003%) was identifi ed and this was due to an error in patient identifi cation in the ward. Other specifi ed reactions like transfusion-related acute lung injury (TRALI), bacterial infections, Graft verses host disease (GVHD) were not reported. The highest frequency of the reactions occurred in the red cell transfusions which accounted for 111 cases. In conclusion, the incidences of transfusion reactions are low when compared to those reported by other centres.

Original languageEnglish
Pages (from-to)25-29
Number of pages5
JournalMalaysian Journal of Pathology
Volume33
Issue number1
Publication statusPublished - Jun 2011

Fingerprint

Malaysia
Clinical Laboratory Information Systems
Hemoglobinuria
Blood Banks
Transfusion Reaction
Acute Lung Injury
Incidence
Bacterial Infections
Cations
Fever
Retrospective Studies
Transplants

Keywords

  • Audit
  • Blood components
  • Blood transfusion
  • Transfusion reactions

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cell Biology
  • Histology

Cite this

An audit of reported acute transfusion reactions in Universiti Kebangsaan Malaysia Medical Centre. / Rabeya, Y.; Abdul-Kahar, A. H.; Chooi Fun, Leong.

In: Malaysian Journal of Pathology, Vol. 33, No. 1, 06.2011, p. 25-29.

Research output: Contribution to journalArticle

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