Alocasia denudata Engler treatment enhance open wound healing activities in Wistar rat's skin

Mazlyzam Abdul Latif, Mohd Zulasyraf Mohd Zaki, Tai May Leng, Noor Hidayah Abdul Rahman, Siti Aisyah Arshad, Asmah Hamid

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Ethnopharmacological relevance A. denudata is traditionally used to treat various skin disorders, including wounds. It is widely used by the traditional healers as an effective wound treatment. Aim of study This study was done to determine A. denudata treatment effects on open wound healing activities in Wistar rat's skin. Materials and methods 120 Wistar rats (250-300 g) were divided into four main groups, 1.5% and 3% A. denudata stem juice treated group, 10% Solcoseryl® gel treated group as positive control and phosphate buffer saline (PBS) treated group as negative control. Six full thicknesses wounds (6 mm) were induced bilaterally on the dorsal of the rat's skin. Rats were sacrificed on day 1, 3, 6, 10 and 14. The percentage of wound contraction, biochemical estimations, macroscopic observation and histological examinations were done to evaluate the wound healing activities. Results Results showed wounds treated with A. denudata stem juice possess a significant higher rate of wound contraction (p

Original languageEnglish
Pages (from-to)258-267
Number of pages10
JournalJournal of Ethnopharmacology
Volume176
DOIs
Publication statusPublished - 24 Dec 2015

Fingerprint

Alocasia
Wound Healing
Wistar Rats
Skin
Wounds and Injuries
Actihaemyl
Buffers
Gels
Phosphates
Observation

Keywords

  • Alocasia denudata Engler
  • Skin
  • Wound healing

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

Cite this

Alocasia denudata Engler treatment enhance open wound healing activities in Wistar rat's skin. / Abdul Latif, Mazlyzam; Zulasyraf Mohd Zaki, Mohd; May Leng, Tai; Hidayah Abdul Rahman, Noor; Aisyah Arshad, Siti; Hamid, Asmah.

In: Journal of Ethnopharmacology, Vol. 176, 24.12.2015, p. 258-267.

Research output: Contribution to journalArticle

Abdul Latif, Mazlyzam ; Zulasyraf Mohd Zaki, Mohd ; May Leng, Tai ; Hidayah Abdul Rahman, Noor ; Aisyah Arshad, Siti ; Hamid, Asmah. / Alocasia denudata Engler treatment enhance open wound healing activities in Wistar rat's skin. In: Journal of Ethnopharmacology. 2015 ; Vol. 176. pp. 258-267.
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AU - Hidayah Abdul Rahman, Noor

AU - Aisyah Arshad, Siti

AU - Hamid, Asmah

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