Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient

M. A. Shahar, Norasyikin A. Wahab @ A. Rahman, Aini AbAziz, O. Ahmad Marzuki, N. A. Mohd Rusly, Nor Azmi Kamaruddin

Research output: Contribution to journalArticle

Abstract

Histoplasmosis usually affects immunocompromised patients. Histoplasmosis infiltration to the adrenal in an immunocompetent host is rare, more so those who presented with adrenal insufficiency. We report a case of 54-year-old previously fit and healthy man who presented with chronic headache of two months duration that was associated with loss of appetite and weight-loss. He had hypotension, hyponatremia, relative hyperkalemia with morning cortisol of 160 nmol/L. Computed tomography of the adrenals showed bilateral enlarged adrenal glands and biopsy confirmed histoplasmosis infiltration. Treatment successfully ameliorate symptoms of hypocortisolism. This case illustrates that immunocompetent patient is still susceptible to adrenal histoplasmosis resulting in adrenal insufficiency.

Original languageEnglish
Pages (from-to)261-264
Number of pages4
JournalBrunei International Medical Journal
Volume11
Issue number5
Publication statusPublished - 2015

Fingerprint

Histoplasmosis
Adrenal Insufficiency
Headache Disorders
Hyperkalemia
Hyponatremia
Immunocompromised Host
Appetite
Adrenal Glands
Hypotension
Hydrocortisone
Weight Loss
Tomography
Biopsy
Therapeutics

Keywords

  • Adrenal insufficiency
  • Adrenal masses
  • Histoplasmosis
  • Immunocompetent

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Adrenal insufficiency resulting from Histoplasmosis infiltration in an immunocompetent patient. / Shahar, M. A.; A. Wahab @ A. Rahman, Norasyikin; AbAziz, Aini; Ahmad Marzuki, O.; Mohd Rusly, N. A.; Kamaruddin, Nor Azmi.

In: Brunei International Medical Journal, Vol. 11, No. 5, 2015, p. 261-264.

Research output: Contribution to journalArticle

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