Acute Disseminated Encephalomyelitis (ADEM) Presenting with Seizures Secondary to Anti-tetanus Toxin Vaccination

Bin Basri Hamidon, Raymond Azman Ali

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system (CNS) that is known to occur spontaneously in association with specific and non-specific viral illnesses and after vaccination against various pathogens. Although it is often a self-limited monophasic illness, the fatality rate is estimated to be as high as 20%, and many patients suffer residual neurologic impairment1. The diagnosis is mainly based on clinical and radiological findings. The clinical presentation varies from merely an asymptomatic condition to loss of consciousness, seizures, ataxia, optic neuropathy, cranial nerve palsies, and motor dysfunction. MRI of the brain is the single most important diagnostic radiological investigation and can facilitate early diagnosis and prompt treatment. This case report describes a patient with ADEM presenting with only seizures after vaccination with anti-tetanus toxin.

Original languageEnglish
Pages (from-to)780-782
Number of pages3
JournalMedical Journal of Malaysia
Volume58
Issue number5
Publication statusPublished - Dec 2003

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Acute Disseminated Encephalomyelitis
Tetanus Toxin
Vaccination
Seizures
Cranial Nerve Diseases
Asymptomatic Diseases
Optic Nerve Diseases
Unconsciousness
Demyelinating Diseases
Ataxia
Nervous System
Early Diagnosis
Central Nervous System
Brain
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Acute Disseminated Encephalomyelitis (ADEM) Presenting with Seizures Secondary to Anti-tetanus Toxin Vaccination. / Hamidon, Bin Basri; Ali, Raymond Azman.

In: Medical Journal of Malaysia, Vol. 58, No. 5, 12.2003, p. 780-782.

Research output: Contribution to journalArticle

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