A systematic review on pharmacological activities of 4-methylumbelliferon

Yasmeen Al-Majedy, Abdul Amir H. Kadhum, Hiba Ibraheem, Ahmed Al-Amiery, Ahmed Abdel Moneim, Abu Bakar Mohamad

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Umbelliferon, the natural crenelated coumarin distributed in the plants of a piaceae family, has shown various biological activities, especially as a cancer chemo preventive agent. Coumarins have been categorized as a member of family of benzo-pyrone, that consist of pyrone ring united to benzene ring. The benzo-pyrones may be sectioned to alfa type that coumarins belong and the gama type that flavonoids have been major members. Coumarins are chemical entity which has being synthesized in the past few years many forms of its derivatives; the entity provides the principal origin of motivating to numerous chemist to investigate its diverse medical efforts especially with regards to the anticoagulant activity. In present article we review recent 4-Methylumbelliferon, (4-MU) that are synthesized with it pharmacological activities antioxidant, anti-inflammatory, antimicrobial activity, ant hepatitis, hepatoprotective, anticancer, antipyretic and analgesic activity.

Original languageEnglish
Pages (from-to)49-54
Number of pages6
JournalSystematic Reviews in Pharmacy
Volume9
Issue number1
DOIs
Publication statusPublished - 1 Jan 2018

Fingerprint

Pyrones
Coumarins
Pharmacology
Apiaceae
Antipyretics
Ants
Benzene
Flavonoids
Anticoagulants
Hepatitis
Analgesics
Anti-Inflammatory Agents
Antioxidants
Neoplasms

Keywords

  • 4-Methylumbelliferon
  • 4-MU
  • 7-hydroxy-4-mehtyl coumarin
  • Anti-inflammatory
  • Anticoagulant
  • Anticonvulsant activity
  • Antimicrobial
  • Antioxidant
  • Antitumor

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Al-Majedy, Y., Kadhum, A. A. H., Ibraheem, H., Al-Amiery, A., Moneim, A. A., & Mohamad, A. B. (2018). A systematic review on pharmacological activities of 4-methylumbelliferon. Systematic Reviews in Pharmacy, 9(1), 49-54. https://doi.org/10.5530/srp.2018.1.10

A systematic review on pharmacological activities of 4-methylumbelliferon. / Al-Majedy, Yasmeen; Kadhum, Abdul Amir H.; Ibraheem, Hiba; Al-Amiery, Ahmed; Moneim, Ahmed Abdel; Mohamad, Abu Bakar.

In: Systematic Reviews in Pharmacy, Vol. 9, No. 1, 01.01.2018, p. 49-54.

Research output: Contribution to journalReview article

Al-Majedy, Y, Kadhum, AAH, Ibraheem, H, Al-Amiery, A, Moneim, AA & Mohamad, AB 2018, 'A systematic review on pharmacological activities of 4-methylumbelliferon', Systematic Reviews in Pharmacy, vol. 9, no. 1, pp. 49-54. https://doi.org/10.5530/srp.2018.1.10
Al-Majedy Y, Kadhum AAH, Ibraheem H, Al-Amiery A, Moneim AA, Mohamad AB. A systematic review on pharmacological activities of 4-methylumbelliferon. Systematic Reviews in Pharmacy. 2018 Jan 1;9(1):49-54. https://doi.org/10.5530/srp.2018.1.10
Al-Majedy, Yasmeen ; Kadhum, Abdul Amir H. ; Ibraheem, Hiba ; Al-Amiery, Ahmed ; Moneim, Ahmed Abdel ; Mohamad, Abu Bakar. / A systematic review on pharmacological activities of 4-methylumbelliferon. In: Systematic Reviews in Pharmacy. 2018 ; Vol. 9, No. 1. pp. 49-54.
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