A scanning electron microscopic study of in vivo tissue engineered respiratory epithelium in sheep.

Mohd Heikal Mohd Yunus, B. S. Aminuddin, J. Jeevanan, H. C. Chen, S. Sharifah, Ruszymah Idrus

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Normal tracheal mucociliary clearance is the key to maintaining the health and defense of respiratory airway. Therefore the present of cilia and mucous blanket are important for tracheal epithelium to function effectively. In the present study, we prepared a tissue engineered respiratory epithelium construct (TEREC) made of autologous respiratory epithelium cells, fibroblast and fibrin from sheep owns blood which replaced a created tracheal mucosal defect. Scanning electron microscopy (SEM) showed encouraging result where immature cilia were present on the surface of TEREC. This result indicates that engineered respiratory epithelium was able to function as normal tissue.

Original languageEnglish
Pages (from-to)34
Number of pages1
JournalThe Medical journal of Malaysia
Volume63 Suppl A
Publication statusPublished - Jul 2008

Fingerprint

Respiratory Mucosa
Sheep
Electrons
Cilia
Mucociliary Clearance
Fibrin
Electron Scanning Microscopy
Epithelium
Fibroblasts
Health

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A scanning electron microscopic study of in vivo tissue engineered respiratory epithelium in sheep. / Mohd Yunus, Mohd Heikal; Aminuddin, B. S.; Jeevanan, J.; Chen, H. C.; Sharifah, S.; Idrus, Ruszymah.

In: The Medical journal of Malaysia, Vol. 63 Suppl A, 07.2008, p. 34.

Research output: Contribution to journalArticle

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