A review of bacterial cellulose-based drug delivery systems: Their biochemistry, current approaches and future prospects

Muhammad Mustafa Abeer, Mohd Cairul Iqbal Mohd Amin, Claire Martin

Research output: Contribution to journalArticle

117 Citations (Scopus)

Abstract

Objectives The field of pharmaceutical technology is expanding rapidly because of the increasing number of drug delivery options. Successful drug delivery is influenced by multiple factors, one of which is the appropriate identification of materials for research and engineering of new drug delivery systems. Bacterial cellulose (BC) is one such biopolymer that fulfils the criteria for consideration as a drug delivery material. Key findings BC showed versatility in terms of its potential for in-situ modulation, chemical modification after synthesis and application in the biomedical field, thus expanding the current, more limited view of BC and facilitating the investigation of its potential for application in drug delivery. Summary Cellulose, which is widely available in nature, has numerous applications. One of the applications is that of BC in the pharmaceutical and biomedical fields, where it has been primarily applied for transdermal formulations to improve clinical outcomes. This review takes a multidisciplinary approach to consideration of the feasibility and potential benefits of BC in the development of other drug delivery systems for various routes of administration.

Original languageEnglish
Pages (from-to)1047-1061
Number of pages15
JournalJournal of Pharmacy and Pharmacology
Volume66
Issue number8
DOIs
Publication statusPublished - 2014

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Drug Delivery Systems
Cellulose
Biochemistry
Pharmaceutical Preparations
Pharmaceutical Technology
Biopolymers
Research

Keywords

  • bacterial cellulose
  • drug delivery
  • hydrogel
  • nanocellulose
  • nata de coco

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science

Cite this

A review of bacterial cellulose-based drug delivery systems : Their biochemistry, current approaches and future prospects. / Abeer, Muhammad Mustafa; Mohd Amin, Mohd Cairul Iqbal; Martin, Claire.

In: Journal of Pharmacy and Pharmacology, Vol. 66, No. 8, 2014, p. 1047-1061.

Research output: Contribution to journalArticle

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