A review of adult head and neck soft tissue sarcoma in a tertiary centre

Malaysia experience

Salman Amiruddin, Mohd Razif Muhamad Yunus, Marina Mat Baki

Research output: Contribution to journalArticle

Abstract

Background: Head and neck tissue sarcoma are rare with potential high morbidity and mortality. The purpose of the present study was to present these cases and determine the optimal treatment for adult patients with head and neck soft tissue sarcomas. Methods: It is a retrospective study of adult head and neck soft tissue sarcoma conducted in the Department of Otorhinolaryngology at Universiti Kebangsaan Malaysia Medical Centre (UKMMC) which is one of the national referral center within the period of 16 years from 1998 till 2014. Results: Fourteen cases were reviewed in which7 histopathological variations of soft tissue sarcomas were identified. Local control after surgery alone or combined with radiotherapy was obtained in 50 % of the patients which is influenced by histologic grade, tumor size, and surgical margins. Patients with high-grade tumors or positive margins have improved local control if adjuvant radiotherapy is used. Distant metastases occurred in 14.2 % of patients and the 5-year survival rate was 50 %. Conclusions: The optimal treatment for adult head and neck soft tissue sarcomas is surgery. Adjuvant radiotherapy improves outcomes for those with high-grade tumors or positive margins.

Original languageEnglish
Pages (from-to)69-76
Number of pages8
JournalBangladesh Journal of Medical Science
Volume16
Issue number1
DOIs
Publication statusPublished - 2017

Fingerprint

Malaysia
Sarcoma
Neck
Head
Adjuvant Radiotherapy
Neoplasms
Otolaryngology
Radiotherapy
Referral and Consultation
Survival Rate
Retrospective Studies
Neoplasm Metastasis
Morbidity
Mortality
Therapeutics

Keywords

  • Chemotherapy
  • Head and neck
  • Margin
  • Prognosis
  • Radiotherapy
  • Soft tissue sarcoma
  • Surgery

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A review of adult head and neck soft tissue sarcoma in a tertiary centre : Malaysia experience. / Amiruddin, Salman; Muhamad Yunus, Mohd Razif; Mat Baki, Marina.

In: Bangladesh Journal of Medical Science, Vol. 16, No. 1, 2017, p. 69-76.

Research output: Contribution to journalArticle

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