A rare case report on spinal paraganglioma

Research output: Contribution to journalArticle

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Abstract

Paragangliomas are tumors that arise from the paraganglia cells of the autonomic nervous system, which are in turn derived from the neural crest. Approximately 80%-90% of these tumors arise in the glomus jugulare or carotid bodies. Paragangliomas arising within the spinal canal are rare, and when they occur are usually found in the intradural, extramedullary compartment and in the lumbosacral region. Large lumbar paragangliomas are very rare. We report a case of a 58-year-old woman who had a history of back pain and radiculopathy was found to have a primary lumbar paraganglioma presenting with spinal cord compression. In this case, a large vascularised paraganglioma measuring 13.0 cm x 15.0 cm was occupying L2-L4 vertebrae body extending to paravertebral space and spinal canal with distant metastasis to left 5th rib in CT scan. Total debulking procedure was impossible because of its high vascularity. Thus angiography and embolization was carried out instead. Seventy five percent reduction in vascular supply was noted after 2nd embolization procedure. We believe that paragangliomas should be included in the diagnosis of intraosseous spinal tumors. They are highly vascular and difficult to excise in total. Optimal treatment of the lesions can be difficult because of their hypervascular nature and high morbidity associated with complete surgical resection. Preoperative embolization, surgical resection if possible, and radiation therapy should be combined.

Original languageEnglish
Pages (from-to)76-77
Number of pages2
JournalInternational Medical Journal
Volume18
Issue number1
Publication statusPublished - Mar 2011

Fingerprint

Paraganglioma
Spinal Canal
Blood Vessels
Glomus Jugulare
Carotid Body
Lumbosacral Region
Neoplasms
Spinal Cord Compression
Radiculopathy
Neural Crest
Autonomic Nervous System
Ribs
Back Pain
Angiography
Spine
Radiotherapy
Neoplasm Metastasis
Morbidity

Keywords

  • Embolization
  • Lumbar paraganglioma
  • Paraganglioma
  • Spinal tumor

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A rare case report on spinal paraganglioma. / Htwe, Ohnmar; Zakaria, Rozman; Selvi Naicker, Amaramalar.

In: International Medical Journal, Vol. 18, No. 1, 03.2011, p. 76-77.

Research output: Contribution to journalArticle

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