A new symmetrical tetramer oligostilbenoid containing tetrahydrofuran ring from the stem bark of Dryobalanops lanceolata

Norizan Ahmat, Agustono Wibowo, Sharifah Aminah Syed Mohamad, Anis Lou Muhammad Low, Adila Sahida Sufian, Muhd Izwan Muhd Yusof, Jalifah Latip

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A new tetramer oligostilbenoid possessing tetrahydrofuran ring, malaysianol C (1), was isolated from the acetone extract of the stem bark of Dryobalanops lanceolata, together with four known oligostilbenoids nepalensinol E (2), ε-viniferin (3), laevifonol (4), and ampelopsin F (5). The structures of isolated compounds were elucidated on the basis of spectral evidence. The antibacterial activity of the isolated compounds was evaluated using resazurin microtitre-plate assay, whereas the cytotoxic activity was tested using MTT assay. The plausible biogenetic routes of the isolated compounds are also discussed.

Original languageEnglish
Pages (from-to)1099-1107
Number of pages9
JournalJournal of Asian Natural Products Research
Volume16
Issue number11
DOIs
Publication statusPublished - 2 Nov 2014

Fingerprint

Dipterocarpaceae
Acetone
Assays
resazurin
tetrahydrofuran
malaysianol C
ampelopsin

Keywords

  • antibacterial
  • cytotoxicity
  • Dipterocarpaceae
  • Dryobalanops lanceolata
  • malaysianol C
  • oligostilbenoid

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology
  • Pharmaceutical Science
  • Analytical Chemistry
  • Organic Chemistry
  • Molecular Medicine
  • Complementary and alternative medicine
  • Medicine(all)

Cite this

A new symmetrical tetramer oligostilbenoid containing tetrahydrofuran ring from the stem bark of Dryobalanops lanceolata. / Ahmat, Norizan; Wibowo, Agustono; Mohamad, Sharifah Aminah Syed; Low, Anis Lou Muhammad; Sufian, Adila Sahida; Yusof, Muhd Izwan Muhd; Latip, Jalifah.

In: Journal of Asian Natural Products Research, Vol. 16, No. 11, 02.11.2014, p. 1099-1107.

Research output: Contribution to journalArticle

Ahmat, Norizan ; Wibowo, Agustono ; Mohamad, Sharifah Aminah Syed ; Low, Anis Lou Muhammad ; Sufian, Adila Sahida ; Yusof, Muhd Izwan Muhd ; Latip, Jalifah. / A new symmetrical tetramer oligostilbenoid containing tetrahydrofuran ring from the stem bark of Dryobalanops lanceolata. In: Journal of Asian Natural Products Research. 2014 ; Vol. 16, No. 11. pp. 1099-1107.
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AU - Low, Anis Lou Muhammad

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