Abstract
A new tetramer oligostilbenoid possessing tetrahydrofuran ring, malaysianol C (1), was isolated from the acetone extract of the stem bark of Dryobalanops lanceolata, together with four known oligostilbenoids nepalensinol E (2), ε-viniferin (3), laevifonol (4), and ampelopsin F (5). The structures of isolated compounds were elucidated on the basis of spectral evidence. The antibacterial activity of the isolated compounds was evaluated using resazurin microtitre-plate assay, whereas the cytotoxic activity was tested using MTT assay. The plausible biogenetic routes of the isolated compounds are also discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 1099-1107 |
| Number of pages | 9 |
| Journal | Journal of Asian Natural Products Research |
| Volume | 16 |
| Issue number | 11 |
| DOIs | |
| Publication status | Published - 2 Nov 2014 |
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Keywords
- antibacterial
- cytotoxicity
- Dipterocarpaceae
- Dryobalanops lanceolata
- malaysianol C
- oligostilbenoid
ASJC Scopus subject areas
- Drug Discovery
- Pharmacology
- Pharmaceutical Science
- Analytical Chemistry
- Organic Chemistry
- Molecular Medicine
- Complementary and alternative medicine
- Medicine(all)
Cite this
A new symmetrical tetramer oligostilbenoid containing tetrahydrofuran ring from the stem bark of Dryobalanops lanceolata. / Ahmat, Norizan; Wibowo, Agustono; Mohamad, Sharifah Aminah Syed; Low, Anis Lou Muhammad; Sufian, Adila Sahida; Yusof, Muhd Izwan Muhd; Latip, Jalifah.
In: Journal of Asian Natural Products Research, Vol. 16, No. 11, 02.11.2014, p. 1099-1107.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A new symmetrical tetramer oligostilbenoid containing tetrahydrofuran ring from the stem bark of Dryobalanops lanceolata
AU - Ahmat, Norizan
AU - Wibowo, Agustono
AU - Mohamad, Sharifah Aminah Syed
AU - Low, Anis Lou Muhammad
AU - Sufian, Adila Sahida
AU - Yusof, Muhd Izwan Muhd
AU - Latip, Jalifah
PY - 2014/11/2
Y1 - 2014/11/2
N2 - A new tetramer oligostilbenoid possessing tetrahydrofuran ring, malaysianol C (1), was isolated from the acetone extract of the stem bark of Dryobalanops lanceolata, together with four known oligostilbenoids nepalensinol E (2), ε-viniferin (3), laevifonol (4), and ampelopsin F (5). The structures of isolated compounds were elucidated on the basis of spectral evidence. The antibacterial activity of the isolated compounds was evaluated using resazurin microtitre-plate assay, whereas the cytotoxic activity was tested using MTT assay. The plausible biogenetic routes of the isolated compounds are also discussed.
AB - A new tetramer oligostilbenoid possessing tetrahydrofuran ring, malaysianol C (1), was isolated from the acetone extract of the stem bark of Dryobalanops lanceolata, together with four known oligostilbenoids nepalensinol E (2), ε-viniferin (3), laevifonol (4), and ampelopsin F (5). The structures of isolated compounds were elucidated on the basis of spectral evidence. The antibacterial activity of the isolated compounds was evaluated using resazurin microtitre-plate assay, whereas the cytotoxic activity was tested using MTT assay. The plausible biogenetic routes of the isolated compounds are also discussed.
KW - antibacterial
KW - cytotoxicity
KW - Dipterocarpaceae
KW - Dryobalanops lanceolata
KW - malaysianol C
KW - oligostilbenoid
UR - http://www.scopus.com/inward/record.url?scp=84911952425&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84911952425&partnerID=8YFLogxK
U2 - 10.1080/10286020.2014.938059
DO - 10.1080/10286020.2014.938059
M3 - Article
C2 - 25034352
AN - SCOPUS:84911952425
VL - 16
SP - 1099
EP - 1107
JO - Journal of Asian Natural Products Research
JF - Journal of Asian Natural Products Research
SN - 1028-6020
IS - 11
ER -