A new sesquiterpenoid from Scaphium macropodum (Miq.) Beumee

L. M Ramadhan Al Muqarrabun, Norizan Ahmat, S. Ruzaina S Aris, Nurdiana Shamsulrijal, Syarul Nataqain Baharum, Rafidah Ahmad, A. Rifki Rosandy, M. Nazip Suratman, H. Takayama

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A new sesquiterpenoid, malayscaphiol (1), and three known compounds, lupeol (2), lupenone (3) and stigmasterol (4), were isolated from the methanolic extract of the stem bark of Scaphium macropodum. The structures of the isolated compounds were determined using several spectroscopic methods, including UV-vis, FT-IR, 1D and 2D NMR, and mass spectrometer. Major isolated compounds were assayed for cytotoxicity and anti-acetylcholinesterase activities. The chemotaxonomy significance of this plant was also discussed.

Original languageEnglish
Pages (from-to)597-605
Number of pages9
JournalNatural Product Research
Volume28
Issue number9
DOIs
Publication statusPublished - 3 May 2014

Fingerprint

Stigmasterol
lupeol
chemotaxonomy
stigmasterol
Mass spectrometers
Acetylcholinesterase
Cytotoxicity
acetylcholinesterase
spectrometers
sesquiterpenoids
cytotoxicity
bark
Nuclear magnetic resonance
stems
extracts
methodology
Scaphium macropodum
lupenone
malayscaphiol

Keywords

  • anti-acetylcholinesterase
  • cytotoxicity
  • malayscaphiol
  • Scaphium macropodum
  • sesquiterpenoid
  • Sterculiaceae

ASJC Scopus subject areas

  • Plant Science
  • Biochemistry
  • Analytical Chemistry
  • Organic Chemistry

Cite this

Al Muqarrabun, L. M. R., Ahmat, N., Aris, S. R. S., Shamsulrijal, N., Baharum, S. N., Ahmad, R., ... Takayama, H. (2014). A new sesquiterpenoid from Scaphium macropodum (Miq.) Beumee. Natural Product Research, 28(9), 597-605. https://doi.org/10.1080/14786419.2014.886211

A new sesquiterpenoid from Scaphium macropodum (Miq.) Beumee. / Al Muqarrabun, L. M Ramadhan; Ahmat, Norizan; Aris, S. Ruzaina S; Shamsulrijal, Nurdiana; Baharum, Syarul Nataqain; Ahmad, Rafidah; Rosandy, A. Rifki; Suratman, M. Nazip; Takayama, H.

In: Natural Product Research, Vol. 28, No. 9, 03.05.2014, p. 597-605.

Research output: Contribution to journalArticle

Al Muqarrabun, LMR, Ahmat, N, Aris, SRS, Shamsulrijal, N, Baharum, SN, Ahmad, R, Rosandy, AR, Suratman, MN & Takayama, H 2014, 'A new sesquiterpenoid from Scaphium macropodum (Miq.) Beumee', Natural Product Research, vol. 28, no. 9, pp. 597-605. https://doi.org/10.1080/14786419.2014.886211
Al Muqarrabun LMR, Ahmat N, Aris SRS, Shamsulrijal N, Baharum SN, Ahmad R et al. A new sesquiterpenoid from Scaphium macropodum (Miq.) Beumee. Natural Product Research. 2014 May 3;28(9):597-605. https://doi.org/10.1080/14786419.2014.886211
Al Muqarrabun, L. M Ramadhan ; Ahmat, Norizan ; Aris, S. Ruzaina S ; Shamsulrijal, Nurdiana ; Baharum, Syarul Nataqain ; Ahmad, Rafidah ; Rosandy, A. Rifki ; Suratman, M. Nazip ; Takayama, H. / A new sesquiterpenoid from Scaphium macropodum (Miq.) Beumee. In: Natural Product Research. 2014 ; Vol. 28, No. 9. pp. 597-605.
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