Abstract
A new prenylated dihydrochalcone, 2′,4′-dihydroxy-4-methoxy- 3′-prenyldihydrochalcone (1), along with two known compounds, 2′,4′,4-trihydroxy-3′-prenylchalcone (2) and 2′,4-dihydroxy-3′,4′-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1-3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1-3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.
| Original language | English |
|---|---|
| Pages (from-to) | 321-324 |
| Number of pages | 4 |
| Journal | Journal of Natural Medicines |
| Volume | 62 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Jul 2008 |
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Keywords
- Antioxidant
- Artocarpus lowii
- Chalcone
- DPPH
- ESR
- Leaves
- Moraceae
ASJC Scopus subject areas
- Organic Chemistry
- Complementary and alternative medicine
- Drug Discovery
- Pharmaceutical Science
Cite this
A new prenylated dihydrochalcone from the leaves of Artocarpus lowii. / Jamil, Shajarahtunnur; Sirat, Hasnah Mohd; Jantan, Ibrahim; Aimi, Norio; Kitajima, Mariko.
In: Journal of Natural Medicines, Vol. 62, No. 3, 07.2008, p. 321-324.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A new prenylated dihydrochalcone from the leaves of Artocarpus lowii
AU - Jamil, Shajarahtunnur
AU - Sirat, Hasnah Mohd
AU - Jantan, Ibrahim
AU - Aimi, Norio
AU - Kitajima, Mariko
PY - 2008/7
Y1 - 2008/7
N2 - A new prenylated dihydrochalcone, 2′,4′-dihydroxy-4-methoxy- 3′-prenyldihydrochalcone (1), along with two known compounds, 2′,4′,4-trihydroxy-3′-prenylchalcone (2) and 2′,4-dihydroxy-3′,4′-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1-3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1-3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.
AB - A new prenylated dihydrochalcone, 2′,4′-dihydroxy-4-methoxy- 3′-prenyldihydrochalcone (1), along with two known compounds, 2′,4′,4-trihydroxy-3′-prenylchalcone (2) and 2′,4-dihydroxy-3′,4′-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1-3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1-3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.
KW - Antioxidant
KW - Artocarpus lowii
KW - Chalcone
KW - DPPH
KW - ESR
KW - Leaves
KW - Moraceae
UR - http://www.scopus.com/inward/record.url?scp=44949265339&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=44949265339&partnerID=8YFLogxK
U2 - 10.1007/s11418-008-0226-3
DO - 10.1007/s11418-008-0226-3
M3 - Article
C2 - 18404311
AN - SCOPUS:44949265339
VL - 62
SP - 321
EP - 324
JO - Natural Medicines
JF - Natural Medicines
SN - 1861-0293
IS - 3
ER -