A new prenylated dihydrochalcone from the leaves of Artocarpus lowii

Shajarahtunnur Jamil, Hasnah Mohd Sirat, Ibrahim Jantan, Norio Aimi, Mariko Kitajima

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

A new prenylated dihydrochalcone, 2′,4′-dihydroxy-4-methoxy- 3′-prenyldihydrochalcone (1), along with two known compounds, 2′,4′,4-trihydroxy-3′-prenylchalcone (2) and 2′,4-dihydroxy-3′,4′-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1-3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1-3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.

Original languageEnglish
Pages (from-to)321-324
Number of pages4
JournalJournal of Natural Medicines
Volume62
Issue number3
DOIs
Publication statusPublished - Jul 2008

Fingerprint

Artocarpus
Chalcone
Scavenging
Electron Spin Resonance Spectroscopy
Spectrometry
Free Radicals
Paramagnetic resonance
Spectrum Analysis
dihydrochalcone
2,2-diphenyl-1-picrylhydrazyl
2',4',4-trihydroxy-3'-prenylchalcone

Keywords

  • Antioxidant
  • Artocarpus lowii
  • Chalcone
  • DPPH
  • ESR
  • Leaves
  • Moraceae

ASJC Scopus subject areas

  • Organic Chemistry
  • Complementary and alternative medicine
  • Drug Discovery
  • Pharmaceutical Science

Cite this

A new prenylated dihydrochalcone from the leaves of Artocarpus lowii. / Jamil, Shajarahtunnur; Sirat, Hasnah Mohd; Jantan, Ibrahim; Aimi, Norio; Kitajima, Mariko.

In: Journal of Natural Medicines, Vol. 62, No. 3, 07.2008, p. 321-324.

Research output: Contribution to journalArticle

Jamil, Shajarahtunnur ; Sirat, Hasnah Mohd ; Jantan, Ibrahim ; Aimi, Norio ; Kitajima, Mariko. / A new prenylated dihydrochalcone from the leaves of Artocarpus lowii. In: Journal of Natural Medicines. 2008 ; Vol. 62, No. 3. pp. 321-324.
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