A fluorescein-derived anthocyanidin-inspired pH sensor

Asier Unciti-Broceta, Muhammad Rahimi Usop, Patricia R. Richardson, Jeffrey G A Walton, Mark Bradley

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

A new multicolor pH-dependent fluorophore was synthesized via Pd-mediated cross-coupling chemistry of the mono-triflate of fluorescein with p-hydroxyphenylboronic acid. The novel indicator, named anthofluorescein, is highly sensitive to pH changes between 7 and 10 and displays a green to red fluorescence shift, making it a valuable candidate for biological studies.

Original languageEnglish
Pages (from-to)3713-3715
Number of pages3
JournalTetrahedron Letters
Volume50
Issue number26
DOIs
Publication statusPublished - 1 Jul 2009
Externally publishedYes

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pH sensors
Anthocyanins
Fluorophores
Fluorescein
Fluorescence
Acids

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Unciti-Broceta, A., Usop, M. R., Richardson, P. R., Walton, J. G. A., & Bradley, M. (2009). A fluorescein-derived anthocyanidin-inspired pH sensor. Tetrahedron Letters, 50(26), 3713-3715. https://doi.org/10.1016/j.tetlet.2009.03.223

A fluorescein-derived anthocyanidin-inspired pH sensor. / Unciti-Broceta, Asier; Usop, Muhammad Rahimi; Richardson, Patricia R.; Walton, Jeffrey G A; Bradley, Mark.

In: Tetrahedron Letters, Vol. 50, No. 26, 01.07.2009, p. 3713-3715.

Research output: Contribution to journalArticle

Unciti-Broceta, A, Usop, MR, Richardson, PR, Walton, JGA & Bradley, M 2009, 'A fluorescein-derived anthocyanidin-inspired pH sensor', Tetrahedron Letters, vol. 50, no. 26, pp. 3713-3715. https://doi.org/10.1016/j.tetlet.2009.03.223
Unciti-Broceta A, Usop MR, Richardson PR, Walton JGA, Bradley M. A fluorescein-derived anthocyanidin-inspired pH sensor. Tetrahedron Letters. 2009 Jul 1;50(26):3713-3715. https://doi.org/10.1016/j.tetlet.2009.03.223
Unciti-Broceta, Asier ; Usop, Muhammad Rahimi ; Richardson, Patricia R. ; Walton, Jeffrey G A ; Bradley, Mark. / A fluorescein-derived anthocyanidin-inspired pH sensor. In: Tetrahedron Letters. 2009 ; Vol. 50, No. 26. pp. 3713-3715.
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