A case report: Metastatic choriocarcinoma to the gum

Research output: Contribution to journalArticle

Abstract

Choriocarcinoma is a rare neoplasia with a tendency of distant metastasis although highly sensitive to chemotherapy renders a good prognosis and outcome. Lungs, liver and cerebral metastasis are commonly implicated with maxillofacial region rarely involved. We illustrate a case of overwhelming metastatic choriocarcinoma to lungs, liver, brain and to the extreme of gum metastasis. Decompressive craniectomy for intracranial bleeding, multiple transfusions to correct anaemia and coagulopathy were done before high-risk-regime chemotherapy. Despite this, due to fulminant multi-organs involvement she finally succumbed to death. In conclusion, gum bleeding in choriocarcinoma may suggest metastasis and poor prognosis.

Original languageEnglish
Pages (from-to)91-92
Number of pages2
JournalSexual and Reproductive Healthcare
Volume2
Issue number2
DOIs
Publication statusPublished - Apr 2011

Fingerprint

Choriocarcinoma
Gingiva
Neoplasm Metastasis
Decompressive Craniectomy
Hemorrhage
Drug Therapy
Lung
Liver
Anemia
Brain
Neoplasms

Keywords

  • Choriocarcinoma
  • Gum
  • Hydratidiform moles
  • Metastatic
  • Methotrexate

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Maternity and Midwifery

Cite this

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AU - Shafiee, Mohamad Nasir

AU - Mohamed Ismail, Nor Azlin

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AU - Kampan, Nirmala @ Chandralega

AU - Omar, Mohd Hashim

AU - Dali, Hatta Mohd

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AB - Choriocarcinoma is a rare neoplasia with a tendency of distant metastasis although highly sensitive to chemotherapy renders a good prognosis and outcome. Lungs, liver and cerebral metastasis are commonly implicated with maxillofacial region rarely involved. We illustrate a case of overwhelming metastatic choriocarcinoma to lungs, liver, brain and to the extreme of gum metastasis. Decompressive craniectomy for intracranial bleeding, multiple transfusions to correct anaemia and coagulopathy were done before high-risk-regime chemotherapy. Despite this, due to fulminant multi-organs involvement she finally succumbed to death. In conclusion, gum bleeding in choriocarcinoma may suggest metastasis and poor prognosis.

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