A case of waterborne contact lens associated Acanthamoeba keratitis from Malaysia: Successful treatment with chlorhexidine and propamidine

Mohamed Kamel Abdul Ghani, F. H. Annuar, N. Ahmad, N. R. Abdullah, J. Hay, D. Seal

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Introduction: Acanthamoeba spp. are ubiquitous free-living protozoa found in a wide range of environmental niches including water and are an important cause of microbial keratitis that may cause severe ocular inflammation and visual loss. The disease is usually associated with contact lens wear and is one of the conditions whose diagnosis is most commonly missed at initial presentation. It is also very resistant to medical therapy especially in advanced disease. Case Report: Since the first case of Acanthamoeba keratitis was reported in Malaysia in 1995, another such patient who was also a contact lens wearer presented to the Universiti Kebangsaan Malaysia Ophthalmology Clinic with similar problems. She, however, presented much earlier and was successfully treated with the combination of topical chlorhexidine and propamidine. Conclusion: This case highlights the importance of early recognition and treatment of Acanthamoeba keratitis as well as the strategies for the prevention of the disease, especially for contact lens wearer. The combination of topical chlorhexidine and propamidine was very effective for treating Acanthamoeba keratitis provided the drugs were continued for a sufficient period.

Original languageEnglish
Pages (from-to)63-65
Number of pages3
JournalInternational Medical Journal
Volume7
Issue number1
Publication statusPublished - 2000

Fingerprint

Acanthamoeba Keratitis
Chlorhexidine
Malaysia
Contact Lenses
Acanthamoeba
Keratitis
Ophthalmology
Therapeutics
Inflammation
Water
Pharmaceutical Preparations
propamidine

Keywords

  • Acanthamoeba keratitis
  • Contact lens
  • Malaysia
  • Treatment
  • Waterborne

ASJC Scopus subject areas

  • Medicine(all)

Cite this

A case of waterborne contact lens associated Acanthamoeba keratitis from Malaysia : Successful treatment with chlorhexidine and propamidine. / Abdul Ghani, Mohamed Kamel; Annuar, F. H.; Ahmad, N.; Abdullah, N. R.; Hay, J.; Seal, D.

In: International Medical Journal, Vol. 7, No. 1, 2000, p. 63-65.

Research output: Contribution to journalArticle

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