A case of persistent hyponatraemia due to reset osmostat

Abdul Ghari Rohana, Norasyikin A. Wahab @ A. Rahman, Z. Suehazlyn, Wong Ming, Norlela Sukor, M. K. Norazmi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We report a case of a 65 year old Malay lady with long-standing diabetes mellitus, who presented to our institution with a one month history of worsening neck pain and progressive upper and lower limb weakness. She was stable despite severe hyponatraemia which was initially treated as syndrome of inappropriate anti-diuretic hormone (SIADH). This was consistent with her underlying illness which was concluded as cervical tuberculosis (TB) with spinal cord compression. She underwent decompression and bone grafting. Despite continuous treatment her serum sodium levels remained low. There were no other problems with her adrenals or thyroid. A water loading and hypertonic saline perfusion test was performed and supported the diagnosis of reset osmostat. Her serum sodium remained below the normal range and she was discharged well.

Original languageEnglish
Pages (from-to)638-640
Number of pages3
JournalMedical Journal of Malaysia
Volume61
Issue number5
Publication statusPublished - Dec 2006

Fingerprint

Hyponatremia
Sodium
Spinal Cord Compression
Bone Transplantation
Neck Pain
Decompression
Serum
Diuretics
Lower Extremity
Diabetes Mellitus
Thyroid Gland
Reference Values
Tuberculosis
Perfusion
Hormones
Water
Therapeutics

Keywords

  • Cervical tuberculosis
  • Hyponatraemia
  • Reset osmostat
  • SIADH
  • Water loading test

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Rohana, A. G., A. Wahab @ A. Rahman, N., Suehazlyn, Z., Ming, W., Sukor, N., & Norazmi, M. K. (2006). A case of persistent hyponatraemia due to reset osmostat. Medical Journal of Malaysia, 61(5), 638-640.

A case of persistent hyponatraemia due to reset osmostat. / Rohana, Abdul Ghari; A. Wahab @ A. Rahman, Norasyikin; Suehazlyn, Z.; Ming, Wong; Sukor, Norlela; Norazmi, M. K.

In: Medical Journal of Malaysia, Vol. 61, No. 5, 12.2006, p. 638-640.

Research output: Contribution to journalArticle

Rohana, AG, A. Wahab @ A. Rahman, N, Suehazlyn, Z, Ming, W, Sukor, N & Norazmi, MK 2006, 'A case of persistent hyponatraemia due to reset osmostat', Medical Journal of Malaysia, vol. 61, no. 5, pp. 638-640.
Rohana, Abdul Ghari ; A. Wahab @ A. Rahman, Norasyikin ; Suehazlyn, Z. ; Ming, Wong ; Sukor, Norlela ; Norazmi, M. K. / A case of persistent hyponatraemia due to reset osmostat. In: Medical Journal of Malaysia. 2006 ; Vol. 61, No. 5. pp. 638-640.
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