• 490 Citations
  • 14 h-Index
19932018
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Research Output 1993 2018

  • 490 Citations
  • 14 h-Index
  • 36 Article
  • 3 Conference contribution
2018
1 Citation (Scopus)
Problem-Based Learning
Learning
Education
Disclosure
Curriculum

Antihypertensive effect of piper sarmentosum in L-NAME-induced hypertensive rats

Alwi, N. A. N. M., Zakaria, Z., Karim, A. A. H., Nordin, N. A. M. M. & Ugusman, A., 1 Oct 2018, In : Sains Malaysiana. 47, 10, p. 2421-2428 8 p.

Research output: Contribution to journalArticle

Piper
NG-Nitroarginine Methyl Ester
Antihypertensive Agents
Nitric Oxide
Blood Pressure
2017
2 Citations (Scopus)
Corn Oil
Blood Vessels
Biomarkers
Blood Pressure
Diet
2015

Correlation between lipid profile and finger photoplethysmogram morphological properties among young men with cardiovascular risk: A preliminary result

Sattar, R. R. M., Chell, K., Aminuddin, A., Omar, N., Zakaria, Z., Ali, M. A. & Nordin, N. A. M. M., 23 Feb 2015, IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet". Institute of Electrical and Electronics Engineers Inc., p. 602-606 5 p. 7047574

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lipids
Cholesterol
Risk assessment
Screening
Blood
9 Citations (Scopus)

The use of Piper sarmentosum leaves aqueous extract (Kadukmy™) as antihypertensive agent in spontaneous hypertensive rats

Mohd Zainudin, M., Zakaria, Z. & Megat Mohd Nordin, N. A., 2015, In : BMC Complementary and Alternative Medicine. 15, p. 54 1 p.

Research output: Contribution to journalArticle

Piper
Antihypertensive Agents
Blood Pressure
Nitric Oxide
Oxidative Stress
2014
5 Citations (Scopus)
Pulse Wave Analysis
C-Reactive Protein
Confidence Intervals
Cardiovascular Diseases
Malaysia

Circulating microRNA as biomarkers for young dyslipidemia men

Norizam, S., Mohd Mokhtar, N., Azmir, A., Nor Anita, M. M. N. & Zakaria, Z., Jun 2014, In : Asian Pacific Journal of Tropical Disease. 4, 3, p. 235 1 p.

Research output: Contribution to journalArticle

Dyslipidemias
MicroRNAs
Biomarkers
Lipid Metabolism
Cholesterol
5 Citations (Scopus)
Phytotherapy
Diabetes Mellitus
Plant Preparations
Diabetes Complications
Complementary Therapies
2 Citations (Scopus)

Identification of circulating microRNAs in young men with central obesity

Azmir, A., Mohd Mokhtar, N., Norizam, S., Nor Anita, MMN. M. N. & Zakaria, Z., Jun 2014, In : Asian Pacific Journal of Tropical Disease. 4, 3, p. 236 1 p.

Research output: Contribution to journalArticle

Abdominal Obesity
MicroRNAs
Blood Circulation
Waist Circumference
Obesity
19 Citations (Scopus)

Role of rutin on nitric oxide synthesis in human umbilical vein endothelial cells

Ugusman, A., Zakaria, Z., Kien Hui, C., Megat Mohd Nordin, N. A. & Abdullah Mahdy, Z., 2014, In : Scientific World Journal. 2014, 169370.

Research output: Contribution to journalArticle

Rutin
Endothelial cells
Human Umbilical Vein Endothelial Cells
nitric oxide
Nitric Oxide
2013
6 Citations (Scopus)

Does oral ingestion of Piper sarmentosum cause toxicity in experimental animals?

Mohd Zainudin, M., Zakaria, Z., Megat Mohd Nordin, N. A. & Othman, F., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 705950.

Research output: Contribution to journalArticle

Piper
Eating
Sprague Dawley Rats
Poisons
Malaysia
9 Citations (Scopus)
Massage
Heart Rate
Blood Pressure
Blood Vessels
Control Groups
6 Citations (Scopus)
Pulse Wave Analysis
Malaysia
C-Reactive Protein
Thigh
Germany
2012

Carotid intima media thickness among young males with cardiovascular risk factors

Aminuddin, A., Salamt, N., Ahmad, A., Azmi, F., Zakaria, Z., Maskon, O., Chell, K. & Megat Mohd Nordin, N. A., 2012, 2012 IEEE-EMBS Conference on Biomedical Engineering and Sciences, IECBES 2012. p. 449-453 5 p. 6498152

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lipoproteins
Blood
Cholesterol
Blood pressure
Oils and fats
3 Citations (Scopus)

Effect of methanolic extract of Piper sarmentosum leaves on neointimal foam cell infiltration in rabbits fed with high cholesterol diet

Amran, A. A., Zakaria, Z., Othman, F., Das, S., Al-Mekhlafi, H. M., Raj, S. & Nordin, N. A. M. M., 2012, In : EXCLI Journal. 11, p. 274-283 10 p.

Research output: Contribution to journalArticle

Piper
foam cells
Foam Cells
high fat diet
infiltration (hydrology)
11 Citations (Scopus)
Piper
Cardiovascular System
Sprague Dawley Rats
Electrons
Body Weight
15 Citations (Scopus)

Flavonoids of Piper sarmentosum and its cytoprotective effects against oxidative stress

Ugusman, A., Zakaria, Z., Kien Hui, C., Nordin, N. A. M. M. & Abdullah Mahdy, Z., 9 Nov 2012, In : EXCLI Journal. 11, p. 705-714 10 p.

Research output: Contribution to journalArticle

Piper
Flavonoids
Rutin
Oxidative Stress
oxidative stress
21 Citations (Scopus)
Piper
Aorta
Control Groups
Diabetes Mellitus
Tunica Intima
3 Citations (Scopus)

Use Piper sarmentosum as an effective antidiabetic supplement in South East Asia: A review

Zar, C. T., Teoh, S. L., Das, S., Zakaria, Z. & Suhaimi, F., 2012, In : Clinica Terapeutica. 163, 6, p. 505-510 6 p.

Research output: Contribution to journalArticle

Piper
Far East
Hypoglycemic Agents
Diabetes Mellitus
Herbal Medicine
2011
25 Citations (Scopus)
Piper
Vascular Cell Adhesion Molecule-1
Intercellular Adhesion Molecule-1
Nutrition
Cholesterol
1 Citation (Scopus)

Effect of graded aerobic exercise training on blood pressure changes in women with elevated blood pressure

Aminuddin, A., Zakaria, Z., Nordin, N. A. M. M., Karim, A. A. H., Maskon, O., Pei, T. S. & Mohd. Fadzilah, F., Sep 2011, In : International Medical Journal. 18, 3, p. 207-211 5 p.

Research output: Contribution to journalArticle

Exercise
Blood Pressure
Ambulatory Blood Pressure Monitoring
Heart Rate
Analysis of Variance
34 Citations (Scopus)
Piper
Human Umbilical Vein Endothelial Cells
NADPH Oxidase
Oxidative Stress
E-Selectin
4 Citations (Scopus)

Problem-based learning: With or without facilitator?

Chuan, T. Y., Rosly, N. B., Bin Zolkipli, M. Z., Wei, N. W., Basheer Ahamed, M. A. B., Binti Mustapha, N. A., Salam, A. & Zakaria, Z., 2011, Procedia - Social and Behavioral Sciences. Vol. 18. p. 394-399 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Problem-Based Learning
learning
Group
Malaysia
Students
41 Citations (Scopus)

Tocotrienol rich fraction supplementation improved lipid profile and oxidative status in healthy older adults: A randomized controlled study

Chin, S. F., Ibahim, J., Makpol, S., Abdul Hamid, N. A., Abdul Latiff, A., Zakaria, Z., Mazlan, M., Mohd Yusof, Y. A., Abdul Karim, A. & Wan Ngah, W. Z., 2011, In : Nutrition and Metabolism. 8, 42.

Research output: Contribution to journalArticle

Tocotrienols
Lipids
Placebos
Vitamin E
Vitamins
1 Citation (Scopus)

Two months aerobic exercise improves endothelial function and reduces oxidative dna damage in women with elevated blood pressure

Aminuddin, A., Zakaria, Z., Mohd Nordin, N. A. M., Hamid Karim, A. A., Maskon, O., Pei, T. S. & Mohd. Fadzilah, F., Apr 2011, In : New Iraqi Journal of Medicine. 7, 1, p. 52-59 8 p.

Research output: Contribution to journalArticle

Exercise
Blood Pressure
Control Groups
von Willebrand Factor
Urine
2010
30 Citations (Scopus)

Aqueous extract of Piper sarmentosum decreases atherosclerotic lesions in high cholesterolemic experimental rabbits

Amran, A. A., Zakaria, Z., Othman, F., Das, S., Raj L, S. & Nordin, N. A. M. M. A., 30 Apr 2010, (Accepted/In press) In : Lipids in Health and Disease. p. 44 1 p.

Research output: Contribution to journalArticle

Piper
Cholesterol
Rabbits
Water
Nutrition
3 Citations (Scopus)
Garcinia
Guinea Pigs
Oxidative Stress
DNA Damage
Aorta
33 Citations (Scopus)

Piper sarmentosum as an antioxidant on oxidative stress in human umbilical vein endothelial cells induced by hydrogen peroxide

Hafizah, A. H., Zakaria, Z., Zulkhairi, A., Mohd Ilham, A., Nor Anita, M. M. N. & Abdullah Mahdy, Z., May 2010, In : Journal of Zhejiang University: Science B. 11, 5, p. 357-365 9 p.

Research output: Contribution to journalArticle

Piper
Oxidative stress
Endothelial cells
Human Umbilical Vein Endothelial Cells
Hydrogen Peroxide
19 Citations (Scopus)

Piper sarmentosum increases nitric oxide production in oxidative stress: A study on human umbilical vein endothelial cells

Ugusman, A., Zakaria, Z., Kien Hui, C. & Nordin, N. A. M. M., 2010, In : Clinics. 65, 7, p. 709-714 6 p.

Research output: Contribution to journalArticle

Piper
Nitric Oxide Synthase Type III
Human Umbilical Vein Endothelial Cells
Nitric Oxide
Oxidative Stress
2009
14 Citations (Scopus)

Effects of Garcinia atroviridis on serum profiles and atherosclerotic lesions in the aorta of guinea pigs fed a high cholesterol diet

Amran, A. A., Zakaria, Z., Othman, F. & Morat, P., Mar 2009, In : Singapore Medical Journal. 50, 3, p. 295-299 5 p.

Research output: Contribution to journalArticle

Garcinia
Aorta
Guinea Pigs
Cholesterol
Diet
2008
26 Citations (Scopus)

Alpha lipoic acid posses dual antioxidant and lipid lowering properties in atherosclerotic-induced New Zealand White rabbit

Zulkhairi, A., Zakaria, Z., Mohamed, J., Sharida, F., Mohd, T. H. B., Hasnah, B., Nazmi, H. M., Osman, K. & Zanariyah, A., Dec 2008, In : Biomedicine and Pharmacotherapy. 62, 10, p. 716-722 7 p.

Research output: Contribution to journalArticle

Thioctic Acid
Antioxidants
Tunica Intima
Rabbits
Lipids
31 Citations (Scopus)

Lipid lowering effect of antioxidant alpha-lipoic acid in experimental atherosclerosis

Amom, Z., Zakaria, Z., Mohamed, J., Azlan, A., Bahari, H., Baharuldin, M. T. H., Moklas, M. A., Osman, K., Asmawi, Z. & Hassan, M. K. N., Sep 2008, In : Journal of Clinical Biochemistry and Nutrition. 43, 2, p. 88-94 7 p.

Research output: Contribution to journalArticle

Thioctic Acid
Atherosclerosis
Antioxidants
Tunica Intima
Lipids
58 Citations (Scopus)

Reduction of DNA damage in older healthy adults by Tri E® Tocotrienol supplementation

Chin, S. F., Hamid, N. A. A., Latiff, A. A., Zakaria, Z., Mazlan, M., Mohd Yusof, Y. A., Karim, A. A., Ibahim, J., Hamid, Z. & Ngah, W. Z. W., Jan 2008, In : Nutrition. 24, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

Tocotrienols
DNA Damage
Sister Chromatid Exchange
Free Radicals
Chromosomes, Human, Pair 4
14 Citations (Scopus)

Role of tocotrienol-rich palm vitamin E on pregnancy and preimplantation embryos in nicotine-treated rats

Mohd Mokhtar, N., Rajikin, M. H. & Zakaria, Z., 2008, In : Biomedical Research. 19, 3, p. 181-184 4 p.

Research output: Contribution to journalArticle

Tocotrienols
Blastocyst
Vitamin E
Nicotine
Rats
2005
6 Citations (Scopus)

Supplementation with alpha lipoic acid improves the in vitro development of embryos in nicotine-treated mice

Rozzana, M. S., Zakaria, Z., Rajikin, M. H., Fadzilah, S. & Zanariyah, A., Jan 2005, In : Biomedical Research. 16, 1, p. 28-32 5 p.

Research output: Contribution to journalArticle

Thioctic Acid
Nicotine
Embryonic Development
Embryonic Structures
Blastocyst
2001
2 Citations (Scopus)
11-beta-Hydroxysteroid Dehydrogenases
Thyroxine
Colon
Kidney
Propylthiouracil
1997
4 Citations (Scopus)

Palm olein oil produces less lipid peroxidation products than soya bean oil

Zakaria, Z., Merican, Z., Khalid, B. A. K., Mohamed, J. & Baharom, S., 1997, In : Asia Pacific Journal of Clinical Nutrition. 6, 2, p. 116-118 3 p.

Research output: Contribution to journalArticle

Soybean Oil
Lipid Peroxidation
Hyperthyroidism
Skeletal Muscle
Malondialdehyde
1995
Tocotrienols
Hyperthyroidism
Muscle Contraction
Propranolol
Lipid Peroxidation
1993
27 Citations (Scopus)

The effects of propranolol on skeletal muscle contraction, lipid peroxidation products and antioxidant activity in experimental hyperthyroidism

Zakaria, Z., Merican, Z., Khalid, B. A. K., Mohamed, J. & Baharom, S., 1993, In : General Pharmacology. 24, 1, p. 195-199 5 p.

Research output: Contribution to journalArticle

Hyperthyroidism
Muscle Contraction
Propranolol
Lipid Peroxidation
Skeletal Muscle