Saiful Effendi Syafruddin

UKM Medical Molecular Biology Institute (UMBI)

Websitehttp://www.ukm.my/umbi/

40 Citations
3 h-Index

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Neoplasms Medicine & Life Sciences

Carcinoma Medicine & Life Sciences

Type 2 Diabetes Mellitus Medicine & Life Sciences

Kidney Medicine & Life Sciences

Kruppel-Like Transcription Factors Medicine & Life Sciences

Renal Cell Carcinoma Medicine & Life Sciences

Ovarian Neoplasms Medicine & Life Sciences

Tumors Chemical Compounds

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Research Output 2014 2019

40 Citations
3 h-Index
10 Article

A KLF6-driven transcriptional network links lipid homeostasis and tumour growth in renal carcinoma

Syafruddin, S. E., Rodrigues, P., Vojtasova, E., Patel, S. A., Zaini, M. N., Burge, J., Warren, A. Y., Stewart, G. D., Eisen, T., Bihary, D., Samarajiwa, S. A. & Vanharanta, S., 1 Dec 2019, In : Nature Communications. 10, 1, 1152.

Research output: Contribution to journal › Article

Open Access

Kruppel-Like Transcription Factors

homeostasis

Gene Regulatory Networks

Renal Cell Carcinoma

lipids

Endogenous HIF2A reporter systems for high-throughput functional screening

Zaini, M. N., Patel, S. A., Syafruddin, S. E., Rodrigues, P. & Vanharanta, S., 1 Dec 2018, In : Scientific Reports. 8, 1, 12063.

Research output: Contribution to journal › Article

Clustered Regularly Interspaced Short Palindromic Repeats

Phenotype

Neoplasms

Libraries

Chromatin

4 Citations (Scopus)

NF-κB–dependent lymphoid enhancer co-option promotes renal carcinoma metastasis

Rodrigues, P., Patel, S. A., Harewood, L., Olan, I., Vojtasova, E., Syafruddin, S. E., Zaini, M. N., Richardson, E. K., Burge, J., Warren, A. Y., Stewart, G. D., Saeb-Parsy, K., Samarajiwa, S. A. & Vanharanta, S., 1 Jul 2018, In : Cancer Discovery. 8, 7, p. 850-865 16 p.

Research output: Contribution to journal › Article

Kidney Neoplasms

Neoplasm Metastasis

Carcinoma

Kidney

Neoplasms

1 Citation (Scopus)

Targeted next-generation sequencing identifies actionable targets in estrogen receptor positive and estrogen receptor negative endometriod endometrial cancer

Suhaimi, S. S., Ab Mutalib, N. S., Khor, S. S., Md Zain, R. R., Syafruddin, S. E., Abu, N., Dali, A. Z. H. M. & A. Jamal, A. R., 13 Jul 2018, In : Frontiers in Pharmacology. 9, JUN, 750.

Research output: Contribution to journal › Article

Endometrial Neoplasms

Estrogen Receptors

Genes

Mutation

Neoplasms

1 Citation (Scopus)

VHL-mediated regulation of CHCHD4 and mitochondrial function

Briston, T., Stephen, J. M., Thomas, L. W., Esposito, C., Chung, Y. L., Syafruddin, S. E., Turmaine, M., Maddalena, L. A., Greef, B., Szabadkai, G., Maxwell, P. H., Vanharanta, S. & Ashcroft, M., 4 Oct 2018, In : Frontiers in Oncology. 8, OCT, 388.

Research output: Contribution to journal › Article

Renal Cell Carcinoma

Electron Transport

Oxygen Consumption

Von Hippel-Lindau Tumor Suppressor Protein

Hypoxia