• 493 Citations
  • 14 h-Index
20102019
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Fingerprint Dive into the research topics where Kok Wai Lam is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Molecular Docking Simulation Medicine & Life Sciences
Curcumin Medicine & Life Sciences
Derivatives Chemical Compounds
Leukocyte Elastase Medicine & Life Sciences
Inhibitory Concentration 50 Medicine & Life Sciences
Farnesyl-Diphosphate Farnesyltransferase Medicine & Life Sciences
Ligands Medicine & Life Sciences
Computer Simulation Medicine & Life Sciences

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Research Output 2010 2019

  • 493 Citations
  • 14 h-Index
  • 49 Article
  • 1 Short survey
  • 1 Review article

Design and synthesis of a novel mPGES-1 lead inhibitor guided by 3D-QSAR CoMFA

Fasihi Mohd Aluwi, M. F., Rullah, K., Koeberle, A., Werz, O., Abdul Razak, N. S., Wei, L. S., Salim, F., Ismail, N. H., Jantan, I. & Lam, K. W., 15 Nov 2019, In : Journal of Molecular Structure. 1196, p. 844-850 7 p.

Research output: Contribution to journalArticle

Curcumin
Macrophages
Biosynthesis
Interleukin-1
Dinoprostone

Insights on the synthesis of asymmetric curcumin derivatives and their biological activities

Khor, P. Y., Mohd Aluwi, M. F. F., Rullah, K. & Lam, K. W., 1 Dec 2019, In : European Journal of Medicinal Chemistry. 183, 111704.

Research output: Contribution to journalShort survey

Curcumin
Bioactivity
Derivatives
Pharmacokinetics
Pharmaceutical Preparations

Palladium-Catalysed Cross-Coupling Reactions for the Synthesis of Chalcones

Rullah, K., Mohd Aluwi, M. F. F., Mohd. Yamin, B., Juan, J. C. & Lam, K. W., 1 Jan 2019, In : Asian Journal of Organic Chemistry. 8, 8, p. 1174-1193 20 p.

Research output: Contribution to journalReview article

Chalcones
Palladium
Chalcone
Scaffolds
Pharmaceutical Chemistry
1 Citation (Scopus)

Hits-to-lead optimization of the natural compound 2,4,6-trihydroxy-3-geranyl-acetophenone (thga) as a potent lox inhibitor: Synthesis, structure-activity relationship (sar) study, and computational assignment

Ng, C. H., Rullah, K., Abas, F., Lam, K. W., Ismail, I. S., Jamaludin, F. & Shaari, K., 30 Sep 2018, In : Molecules. 23, 10, 2509.

Research output: Contribution to journalArticle

Structure-Activity Relationship
inhibitors
Lipoxygenase
analogs
Inhibitory Concentration 50

In silico analysis of Mentha pipertia (phyto-constituents) as HMG coa reductase and squalene synthase inhibitors

Radhakrishnan, N., Lam, K. W. & Intan, S. I., 1 Jan 2018, In : International Food Research Journal. 25, 3, p. 1189-1196 8 p.

Research output: Contribution to journalArticle

Farnesyl-Diphosphate Farnesyltransferase
Mentha
squalene
caffeic acid
Hydroxymethylglutaryl-CoA Synthase