• 171 Citations
  • 7 h-Index
1982 …2019
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Research Output 1982 2019

  • 171 Citations
  • 7 h-Index
  • 35 Article
  • 1 Comment/debate
  • 1 Editorial
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Article
2019

Anti-malarial and cytokine-modulating effects of andrographolide in a murine model of malarial infection

Hassan, W. R. M., Basir, R., Ali, A. H., Embi, N. & Sidek, H. M., Sep 2019, In : Tropical Biomedicine. 36, 3, p. 776-791 16 p.

Research output: Contribution to journalArticle

Antimalarials
Glycogen Synthase Kinase 3
Cytokines
Infection
Malaria
2018

GSK3β inhibition confers survival advantage in Burkholderia pseudomallei-infected hyperglycaemic mice by regulating inflammatory response

Maniam, P., Kalimutho, M., Embi, M. N. & Mohd. Sidek, H., 1 Jan 2018, In : Tropical Biomedicine. 35, 1, p. 228-238 11 p.

Research output: Contribution to journalArticle

Burkholderia pseudomallei
Glycogen Synthase Kinase 3
Obese Mice
Survival
Melioidosis
Burkholderia pseudomallei
Glycogen Synthase Kinase 3
Chloroquine
Antimalarials
Cytokines
2017
1 Citation (Scopus)

Anti-plasmodial and chloroquine resistance suppressive effects of embelin

Zaid, O. I., Majid, R. A., Mohd. Sidek, H., Sabariah, M. N., Al-Zihiry, K., Rahi, S. & Basir, R., 1 Jan 2017, In : Pharmacognosy Magazine. 13, 49, p. S48-S55

Research output: Contribution to journalArticle

Chloroquine
Hemin
Dimethyl Sulfoxide
Malaria
Embelia

Assessment of the inhibitory mechanism of action for a yeast cell-based screening system targeting glycogen synthase kinase-3α (GSK-3α)

Abdul Aziz, D. N. A. F., Mahmud, F., Mohd. Sidek, H., Embi, M. N., Andoh, T. T. & Lee, P. C., 2017, In : Journal of Biological Sciences. 17, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Yeasts
Staurosporine
kenpaullone
Drug Discovery

Glycogen synthase kinase-3β (GSK3β) as a molecular target for cytokine-modulating effect of curcumin in a murine model of acute melioidosis infection

Tan, A., Ganesan, N., Sudi, S., Wong, S. K., Embi, M. N. & Mohd. Sidek, H., 1 Dec 2017, In : Malaysian Applied Biology. 46, 4, p. 43-53 11 p.

Research output: Contribution to journalArticle

Melioidosis
Glycogen Synthase Kinase 3
Curcumin
curcumin
Burkholderia pseudomallei
4 Citations (Scopus)

The Antimalarial Effect of Curcumin Is Mediated by the Inhibition of Glycogen Synthase Kinase-3β

Ali, A. H., Sudi, S., Basir, R., Embi, M. N. & Mohd. Sidek, H., 1 Feb 2017, In : Journal of Medicinal Food. 20, 2, p. 152-161 10 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Curcumin
Antimalarials
Plasmodium berghei
Interleukin-4
2016

Anti-malarial activities of two soil actinomycete isolates from sabah via inhibition of glycogen synthase kinase 3β

Dahari, D. E., Mohamad Salleh, R., Mahmud, F., Ping Chin, L., Embi, M. N. & Mohd. Sidek, H., 2016, In : Tropical Life Sciences Research. 27, 2, p. 53-71 19 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
antimalarials
Actinobacteria
Malaysia
Antimalarials
3 Citations (Scopus)

Antiplasmodial and chloroquine chemosensitizing and resistance reversal effects of coumarin derivatives against Plasmodium falciparum 3D7 and K1

Zaid, O. I., Abd Majid, R., Mohd. Sidek, H., Sabariah, M. N., Rahi, S. & Basir, R., 1 Mar 2016, In : Tropical Biomedicine. 33, 1, p. 14-26 13 p.

Research output: Contribution to journalArticle

Coumarins
Chloroquine
Plasmodium falciparum
Aminocoumarins
Malaria
3 Citations (Scopus)

Mutations of pvdhfr and pvdhps genes in vivax endemic-malaria areas in Kota Marudu and Kalabakan, Sabah

Sastu, U. R., Abdullah, N. R., Norahmad, N. A., Saat, M. N. F., Muniandy, P. K., Jelip, J., Tikuson, M., Yusof, N. & Mohd. Sidek, H., 5 Feb 2016, In : Malaria Journal. 15, 1, 63.

Research output: Contribution to journalArticle

Vivax Malaria
Malaysia
Codon
Mutation
Malaria

Pencirian molekul glikogen sintase kinase-3 Dari Eimeria tenella

Translated title of the contribution: Molecular characterisation of glycogen synthase kinase-3 from Eimeria tenellaYao, P. P., Mohd Raih, M. F., Mohd. Sidek, H., Embi, M. N. & Wan, K. L., 1 Dec 2016, In : Sains Malaysiana. 45, 12, p. 1947-1957 11 p.

Research output: Contribution to journalArticle

Eimeria tenella
tau-protein kinase
coccidiostats
phosphorylation
1 Citation (Scopus)

Phosphorylated and Nonphosphorylated PfMAP2 Are Localized in the Nucleus, Dependent on the Stage of Plasmodium falciparum Asexual Maturation

Dahalan, F. A., Mohd. Sidek, H., Murtey, M. D., Embi, M. N., Ibrahim, J., Fei Tieng, L., Zakaria, N. A. & Abdul-Aziz, N. M., 2016, In : BioMed Research International. 2016, 1645097.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 1
Plasmodium falciparum
Antimalarials
Mitogen-Activated Protein Kinases
Trophozoites
Burkholderia pseudomallei
Glycogen Synthase Kinase 3
Cytokines
Burkholderia Infections
Melioidosis
2015
5 Citations (Scopus)

Andrographolide effect on both Plasmodium falciparum infected and non infected RBCs membranes

Zaid, O. I., Abd Majid, R., Sabariah, M. N., Mohd. Sidek, H., Al-Zihiry, K., Yam, M. F. & Basir, R., 1 Jul 2015, In : Asian Pacific Journal of Tropical Medicine. 8, 7, p. 507-512 6 p.

Research output: Contribution to journalArticle

Plasmodium
Plasmodium falciparum
Merozoites
Membranes
Parasites
3 Citations (Scopus)

Anti-malarial and anti-inflammatory effects of Gleichenia truncata mediated through inhibition of GSK3β

Suhaini, S., Liew, S. Z., Norhaniza, J., Lee, P. C., Jualang, G., Embi, M. N. & Mohd. Sidek, H., 1 Sep 2015, In : Tropical Biomedicine. 32, 3, p. 419-433 15 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Antimalarials
Complex Mixtures
Anti-Inflammatory Agents
Burkholderia pseudomallei
4 Citations (Scopus)

Anti-malarial and anti-inflammatory effects of gynura procumbens are mediated by kaempferol via inhibition of glycogen synthase kinase-3β (GSK3β)

Wong, S. K., Jann, M. L. S., Sudi, S., Hassan, W. R. B. M., Chin, L. P., Embi, M. N. & Mohd. Sidek, H., 1 Oct 2015, In : Sains Malaysiana. 44, 10, p. 1489-1500 12 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Antimalarials
Anti-Inflammatory Agents
Body Weight
Phosphorylation
5 Citations (Scopus)
Streptomyces
Methicillin-Resistant Staphylococcus aureus
Thiazoles
Malaysia
Microbial Sensitivity Tests

Glycogen synthase kinase-3β (GSK3β) inhibition by kaempferol mediates the anti-hyperglycaemic effect of Gynura procumbens

Wong, S. K., Nurul Aiezzah, Z., Embi, M. N. & Mohd. Sidek, H., 2015, In : Malaysian Applied Biology. 44, 2, p. 143-145 3 p.

Research output: Contribution to journalArticle

Gynura procumbens
Glycogen Synthase Kinases
glycemic effect
kaempferol
glycogen synthase kinases
4 Citations (Scopus)

Interleukin-18 antagonism improved histopathological conditions of malaria infection in mice

Jabbarzare, M., Chin, V. K., Talib, H., Yam, M. F., Adam, S. K., Hassan, H., Abdul Majid, R., Mat Taib, C. N., Mohd Moklas, M. A., Taufik Hidayat, M., Mohd. Sidek, H. & Basir, R., 1 Sep 2015, In : Iranian Journal of Parasitology. 10, 3, p. 389-401 13 p.

Research output: Contribution to journalArticle

Interleukin-18
Malaria
Infection
Plasmodium berghei
Inbred ICR Mouse
8 Citations (Scopus)
Burkholderia pseudomallei
Glycogen Synthase Kinase 3
Blood Cells
Cytokines
Bacterial Load
1 Citation (Scopus)

The potential of β carbolin alkaloids to hinder growth and reverse chloroquine resistance in plasmodium falciparum

Ibraheem, Z. O., Abdul Majid, R., Mohd Noor, S., Mohd. Sidek, H. & Basir, R., 1 Oct 2015, In : Iranian Journal of Parasitology. 10, 4, p. 577-583 7 p.

Research output: Contribution to journalArticle

Chloroquine
Plasmodium falciparum
Alkaloids
Growth
Antimalarials
2014
1 Citation (Scopus)

Anti-plasmodial activity of engeletin isolated from Artocarpus scortechinii

Ali, A. H., Hassan, N. M., Shukor, N. I., Embi, M. N., Latip, J. & Mohd. Sidek, H., 2014, In : Malaysian Applied Biology. 43, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

Artocarpus
antimalarials
Inhibitory Concentration 50
extracts
inhibitory concentration 50
3 Citations (Scopus)

Synergistic effects of GSK3 and p38 MAPK inhibitors on growth of plasmodium falciparum ex vivo

Marhalim, L., Embi, M. N. & Mohd. Sidek, H., 2014, In : Malaysian Applied Biology. 43, 1, p. 65-71 7 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Plasmodium falciparum
p38 Mitogen-Activated Protein Kinases
Protein Kinase Inhibitors
mitogen-activated protein kinase
2013
Gracilaria
p38 Mitogen-Activated Protein Kinases
Adenocarcinoma
Cell Death
Ethanol
5 Citations (Scopus)

High prevalence of mutation in the Plasmodium falciparum dhfr and dhps genes in field isolates from Sabah, Northern Borneo

Abdullah, N. R., Norahmad, N. A., Jelip, J., Sulaiman, L. H., Mohd. Sidek, H., Ismail, Z. & Noedl, H., 2013, In : Malaria Journal. 12, 1, 198.

Research output: Contribution to journalArticle

Borneo
Malaysia
Plasmodium falciparum
Mutation
Genes
6 Citations (Scopus)

Inhibition of GSK3 Attenuates the Intracellular Multiplication of Burkholderia pseudomallei and Modulates the Inflammatory Response in Infected Macrophages and A549 Epithelial Lung Cells

Maniam, P., Shiratirat, A. F., Mohd. Sidek, H., Ismail, G. & Embi, M. N., Jun 2013, In : Sains Malaysiana. 42, 6, p. 725-735 11 p.

Research output: Contribution to journalArticle

Burkholderia pseudomallei
Glycogen Synthase Kinase 3
Epithelial Cells
Macrophages
Lung
2012

Changes in hepatic phosphoprotein levels in mice infected with plasmodium berghei

Maniam, P., Hassan, Z. A. A., Embi, M. N. & Mohd. Sidek, H., Jun 2012, In : Sains Malaysiana. 41, 6, p. 721-729 9 p.

Research output: Contribution to journalArticle

Plasmodium berghei
Phosphoproteins
Carbonic Anhydrase III
Liver
Malaria
22 Citations (Scopus)

Glycogen synthase kinase-3β inhibition improved survivability of mice infected with Burkholderia pseudomallei

Tay, T. F., Maheran, M., Too, S. L., Mohd. Sidek, H., Ismail, G. & Embi, M. N., Dec 2012, In : Tropical Biomedicine. 29, 4, p. 551-567 17 p.

Research output: Contribution to journalArticle

Burkholderia pseudomallei
Glycogen Synthase Kinase 3
Cytokines
Interleukin 1 Receptor Antagonist Protein
Spleen
11 Citations (Scopus)

Hypoglycemic effects of Gynura procumbens fractions on streptozotocin- induced diabetic rats involved phosphorylation of GSK3β (Ser-9) in liver

June, C. C., Wen, L. H., Sani, H. A., Latip, J., Gansau, J. A., Chin, L. P., Embi, M. N. & Mohd. Sidek, H., Aug 2012, In : Sains Malaysiana. 41, 8, p. 969-975 7 p.

Research output: Contribution to journalArticle

Streptozocin
Hypoglycemic Agents
Phosphorylation
Glyburide
Liver
10 Citations (Scopus)

In vitro and in vivo anti-plasmodial activities of Gynura procumbens

Vejanan, V., Latip, J., Chin, L. P., Embi, M. N. & Mohd. Sidek, H., Dec 2012, In : Sains Malaysiana. 41, 12, p. 1535-1542 8 p.

Research output: Contribution to journalArticle

Plasmodium berghei
Plant Extracts
Parasites
Plasmodium falciparum
Asteraceae
2011
6 Citations (Scopus)

High prevalence of pfcrt K76T mutants among plasmodium falciparum isolates from Sabah, Malaysia

Norahmad, N. A., Abdullah, N. R., Yaccob, N., Jelip, J., Dony, J. F., Ruslan, K. F., Sulaiman, L. H., Mohd. Sidek, H., Noedl, H. & Ismail, Z., 2011, In : Southeast Asian Journal of Tropical Medicine and Public Health. 42, 6, p. 1322-1326 5 p.

Research output: Contribution to journalArticle

Malaysia
Chloroquine
Plasmodium falciparum
Mutation
DNA
2010
14 Citations (Scopus)

Suppression of Plasmodium berghei parasitemia by LiCl in an animal infection model

Zakaria, N. A., Embi, M. N. & Mohd. Sidek, H., Dec 2010, In : Tropical Biomedicine. 27, 3, p. 624-631 8 p.

Research output: Contribution to journalArticle

Plasmodium berghei
Parasitemia
Animal Models
Chloroquine
Antimalarials
17 Citations (Scopus)

The green MAPKS

K. Nadarajah, K. & Mohd. Sidek, H., 2010, In : Asian Journal of Plant Sciences. 9, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

biotic stress
abiotic stress
1984
34 Citations (Scopus)

Inhibition of synaptosomal enzymes by local anesthetics

Mohd. Sidek, H., Nyquist-Battie, C. & Vanderkooi, G., 7 Sep 1984, In : BBA - General Subjects. 801, 1, p. 26-31 6 p.

Research output: Contribution to journalArticle

Tetracaine
Local Anesthetics
Dibucaine
Adenosine Triphosphatases
Enzymes
1982

Local anesthetic inhibition of F1-ATPase and other enzymes

Vanderkooi, G., Chignell, D., Chazotte, B. & Mohd. Sidek, H., 1982, In : Biophysical Journal. 37, 2 II

Research output: Contribution to journalArticle

Proton-Translocating ATPases
Local Anesthetics
Enzymes