• 1300 Citations
  • 19 h-Index
20042018
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Research Output 2004 2018

  • 1300 Citations
  • 19 h-Index
  • 107 Article
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Article
2018
Hematopoietic Stem Cells
Benzene
Genes
Metabolites
Gene expression
Hep G2 Cells
Stem cells
Mesenchymal Stromal Cells
Liver
Regeneration

Optimization of the static human osteoblast/osteoclast co-culture system

Jolly, J. J., Chin, K. Y., Farhana, M. F. N., Alias, E., Chua, K. H., Hasan, W. N. W. & Ima-Nirwana, S. 1 Mar 2018 In : Iranian Journal of Medical Sciences. 43, 2, p. 208-213 6 p.

Research output: Contribution to journalArticle

Bone Remodeling
Osteoclasts
Coculture Techniques
Osteoblasts
Bone and Bones
Piper
Vascular Cell Adhesion Molecule-1
Human Umbilical Vein Endothelial Cells
Intercellular Adhesion Molecule-1
Tumor Necrosis Factor-alpha
2017

Acanthamoeba-mediated cytopathic effect correlates with MBP and AhLBP mRNA expression

Ng, S. L., Nordin, A., Abd Ghafar, N., Suboh, Y., Ab Rahim, N. & Chua, K. H. 28 Dec 2017 In : Parasites and Vectors. 10, 1, 0625

Research output: Contribution to journalArticle

Acanthamoeba
Messenger RNA
Acanthamoeba Keratitis
Genotype
Keratitis
Tocotrienols
Omeprazole
Intercellular Signaling Peptides and Proteins
Stomach
Transforming Growth Factor alpha
1 Citations

Effect of alginate concentration on chondrogenesis of co-cultured human adipose-derived stem cells and nasal chondrocytes: A biological study

Ewa-Choy, Y. W., Pingguan-Murphy, B., Abdul-Ghani, N. A., Jahendran, J. & Chua, K. H. 17 Oct 2017 In : Biomaterials Research. 21, 1

Research output: Contribution to journalArticle

Chondrogenesis
Alginate
Chondrocytes
Stem cells
Nose

Piper betle L. Modulates Senescence-Associated Genes Expression in Replicative Senescent Human Diploid Fibroblasts

Durani, L. W., Khor, S. C., Tan, J. K., Chua, K. H., Mohd Yusof, Y. A. & Makpol, S. 2017 In : BioMed Research International. 2017, 6894026

Research output: Contribution to journalArticle

Piper betle
Fibroblasts
Diploidy
Gene expression
Gene Expression

The Use of Engineered Bilayered Skin (MyDermTM) in the Management of Massive Skin Defect in Grade III Gustilo-Anderson Open Fracture

Mohamed Haflah, N. H., Ng, M. H., Mohd Yunus, M. H., Naicker, A. S., Htwe, O., Fahmi, M., Ishak, M. F., Seet, W. T., Khairoji, K. A., Maarof, M., Chua, K. H., Shamsuddin, S. A. & Idrus, R. 1 Sep 2017 In : International Journal of Lower Extremity Wounds. 16, 3, p. 212-216 5 p.

Research output: Contribution to journalArticle

Open Fractures
Tibia
Skin
Wounds and Injuries
Tibial Arteries

Tocotrienols stimulate insulin secretion of rat pancreatic isolated islets in a dynamic culture

Chia, L. L., Jantan, I. & Chua, K. H. 1 Jan 2017 In : Current Pharmaceutical Biotechnology. 18, 7, p. 560-568 9 p.

Research output: Contribution to journalArticle

Tocotrienols
Potassium Chloride
Islets of Langerhans
Insulin
Glucose
2016
1 Citations

Acacia honey accelerates in vitro corneal ulcer wound healing model

Abd Ghafar, N., Ker-Woon, C., Hui, C. K., Mohd Yusof, Y. A. & Wan Ngah, W. Z. 29 Jul 2016 In : BMC Complementary and Alternative Medicine. 16, 1, 259

Research output: Contribution to journalArticle

Acacia
Corneal Ulcer
Honey
Wound Healing
Aldehyde Dehydrogenase
1 Citations

Assessment of tumourigenic potential in long-term cryopreserved human adipose-derived stem cells

Yong, K. W., Safwani, W. K. Z. W., Xu, F., Zhang, X., Choi, J. R., Abas, W. A. B. W., Omar, S. Z., Azmi, M. A. N., Chua, K. H. & Pingguan-Murphy, B. 2016 (Accepted/In press) In : Journal of Tissue Engineering and Regenerative Medicine.

Research output: Contribution to journalArticle

Stem cells
Mesenchymal Stromal Cells
Stem Cells
Chromosome Aberrations
Cryoprotective Agents
1 Citations

Chondrogenesis of human adipose derived stem cells for future microtia repair using co-culture technique

Goh, B. S., Che Omar, S. N., Ubaidah, M. A., Saim, L., Sulaiman, S. & Chua, K. H. 29 Nov 2016 (Accepted/In press) In : Acta Oto-Laryngologica. p. 1-10 10 p.

Research output: Contribution to journalArticle

Chondrogenesis
Culture Techniques
Coculture Techniques
Stem Cells
Chondrocytes
3 Citations

Effects of tocotrienols on insulin secretion-associated genes expression of rat pancreatic islets in a dynamic culture

Chia, L. L., Jantan, I., Chua, K. H., Lam, K. W., Rullah, K. & Aluwi, M. F. M. 30 Aug 2016 In : Frontiers in Pharmacology. 7, AUG, 291

Research output: Contribution to journalArticle

Tocotrienols
Islets of Langerhans
Insulin
Gene Expression
Glucose
6 Citations

Enhanced in vitro angiogenic behaviour of human umbilical vein endothelial cells on thermally oxidized TiO 2 nanofibrous surfaces

Tan, A. W., Liau, L. L., Chua, K. H., Ahmad, R., Akbar, S. A. & Pingguan-Murphy, B. 17 Feb 2016 In : Scientific Reports. 6, 21828

Research output: Contribution to journalArticle

Human Umbilical Vein Endothelial Cells
Bone and Bones
Vascular Endothelial Growth Factor A
Intercellular Signaling Peptides and Proteins
CD31 Antigens
2 Citations
Corneal Keratocytes
Honey
Phenotype
Gene Expression
Immunohistochemistry
Hydrogen Peroxide
Hepatocytes
Up-Regulation
Gene Expression
Wounds and Injuries

γ-Tocotrienol prevents cell cycle arrest in aged human fibroblast cells through p16INK4a pathway

Zainuddin, A., Chua, K. H., Tan, J. K., Jaafar, F. & Makpol, S. 14 Oct 2016 (Accepted/In press) In : Journal of Physiology and Biochemistry. p. 1-7 7 p.

Research output: Contribution to journalArticle

Fibroblasts
Cell Cycle Checkpoints
Diploidy
Cell Aging
Cells
2015
4 Citations
Tantalum
Chondrocytes
Fibrin
Cartilage
Rabbits
4 Citations

Differential osteogenic potential of human adipose-derived stem cells co-cultured with human osteoblasts on polymeric microfiber scaffolds

Rozila, I., Azari, P., Munirah, S., Wan Safwani, W. K. Z., Gan, S. N., Nur Azurah, A. G., Jahendran, J., Pingguan-Murphy, B. & Chua, K. H. 2015 (Accepted/In press) In : Journal of Biomedical Materials Research - Part A.

Research output: Contribution to journalArticle

Osteoblasts
Stem cells
Scaffolds
Durapatite
Hydroxyapatite

Effect of Growth Factor Supplementation on the Hair Cell Specific Markers of Cells Harvested from Basilar Membrane

Ubaidah, M. A. Z., Chua, K. H. U., Ami, M., Zainal, A., Saim, A., Saim, L., Lokanathan, Y. & Haji Idrus, R. B. I. 1 Apr 2015 In : The journal of international advanced otology. 11, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

Basilar Membrane
Intercellular Signaling Peptides and Proteins
Calbindin 2
Nestin
Stem Cells
3 Citations

Electrospun Biopolyesters as Drug Screening Platforms for Corneal Keratocytes

Azari, P., Luan, N. S., Gan, S. N., Yahya, R., Wong, C. S., Chua, K. H. & Pingguan-Murphy, B. 22 Nov 2015 In : International Journal of Polymeric Materials and Polymeric Biomaterials. 64, 15, p. 785-791 7 p.

Research output: Contribution to journalArticle

Polycaprolactone
Screening
Pharmaceutical Preparations
Acids
Cell proliferation
17 Citations

In situ normoxia enhances survival and proliferation rate of human adipose tissue-derived stromal cells without increasing the risk of tumourigenesis

Choi, J. R., Pingguan-Murphy, B., Abas, W. A. B. W., Yong, K. W., Poon, C. T., Azmi, A. N., Omar, S. Z., Chua, K. H., Xu, F. & Safwani, W. K. Z. W. 23 Jan 2015 In : PLoS One. 10, 1, e0115034

Research output: Contribution to journalArticle

normoxia
stromal cells
Stromal Cells
adipose tissue
Adipose Tissue
31 Citations

Phenotypic and Functional Characterization of Long-Term Cryopreserved Human Adipose-derived Stem Cells

Yong, K. W., Pingguan-Murphy, B., Xu, F., Abas, W. A. B. W., Choi, J. R., Omar, S. Z., Azmi, M. A. N., Chua, K. H. & Safwani, W. K. Z. W. 15 Apr 2015 In : Scientific Reports. 5, 9596

Research output: Contribution to journalArticle

Dimethyl Sulfoxide
Stem Cells
Cryoprotective Agents
Cryopreservation
Serum
5 Citations
Tocotrienols
tocotrienols
Biomarkers
lesions (animal)
biomarkers
5 Citations

The effects of acacia honey on in vitro corneal abrasion wound healing model

Ker-Woon, C., Ghafar, N. A., Kien Hui, C., Yusof, Y. A. M. & Ngah, W. Z. W. 18 Feb 2015 In : BMC Cell Biology. 16, 1, 53

Research output: Contribution to journalArticle

Acacia
Honey
Wound Healing
Epithelial Cells
Wounds and Injuries
2 Citations

The formation of human auricular cartilage from microtic tissue: An in vivo study

Ishak, M. F. B., See, G. B., Hui, C. K., Abdullah, A. B., Saim, L. B., Saim, A. B. & Idrus, R. B. H. 1 Oct 2015 In : International Journal of Pediatric Otorhinolaryngology. 79, 10, p. 1634-1639 6 p.

Research output: Contribution to journalArticle

Ear Cartilage
Chondrocytes
Cartilage
Staining and Labeling
Collagen Type II
2014
3 Citations

Allogeneic bilayered tissue-engineered skin promotes full-thickness wound healing in ovine model

Idrus, R. B. H., Rameli, M. A. B. P., Cheong, L. K., Xian, L. J., Hui, C. K., Latiff, M. B. A. & Saim, A. B. 2014 In : Biomedical Research. 25, 2, p. 192-198 7 p.

Research output: Contribution to journalArticle

Wound Healing
Sheep
Skin
Tissue
Wounds and Injuries
6 Citations

Comparison of the effects between animal-derived trypsin and recombinant trypsin on human skin cells proliferation, gene and protein expression

Manira, M., Khairul Anuar, K., Seet, W. T., Ahmad Irfan, A. W., Ng, M. H., Chua, K. H., Mohd Heikal, M. Y., Aminuddin, B. S. & Ruszymah, B. H. I. 2014 In : Cell and Tissue Banking. 15, 1, p. 41-49 9 p.

Research output: Contribution to journalArticle

Ethylenediaminetetraacetic acid
Cell proliferation
Trypsin
Skin
Animals
4 Citations

Effect of acacia honey on cultured rabbit corneal keratocytes

Ker-Woon, C., Abd Ghafar, N., Kien Hui, C. & Mohd Yusof, Y. A. 26 May 2014 In : BMC Cell Biology. 15, 1, 19

Research output: Contribution to journalArticle

Corneal Keratocytes
Acacia
Honey
Rabbits
Wound Healing
16 Citations

Full-thickness skin wound healing using autologous keratinocytes and dermal fibroblasts with fibrin: Bilayered versus single-layered substitute

Idrus, R. B. H., Rameli, M. A. B. P., Low, K. C., Law, J. X., Chua, K. H., Abdul Latiff, M. B. & Saim, A. B. 2014 In : Advances in Skin and Wound Care. 27, 4, p. 171-180 10 p.

Research output: Contribution to journalArticle

Fibrin
Keratinocytes
Wound Healing
Fibroblasts
Skin
6 Citations

Impact of adipogenic differentiation on stemness and osteogenic gene expression in extensive culture of human adipose-derived stem cells

Safwani, W. K. Z. W., Makpol, S., Sathapan, S. & Chua, K. 2014 In : Archives of Medical Science. 10, 3, p. 597-606 10 p.

Research output: Contribution to journalArticle

Stem Cells
Gene Expression
Genes
Multipotent Stem Cells
Adipogenesis
45 Citations

Impact of low oxygen tension on stemness, proliferation and differentiation potential of human adipose-derived stem cells

Choi, J. R., Pingguan-Murphy, B., Wan Abas, W. A. B., Noor Azmi, M. A., Omar, S. Z., Chua, K. H. & Wan Safwani, W. K. Z. 30 May 2014 In : Biochemical and Biophysical Research Communications. 448, 2, p. 218-224 7 p.

Research output: Contribution to journalArticle

Stem cells
Stem Cells
Oxygen
Cartilage
Cell Differentiation
14 Citations

Long-term in vitro expansion of human adipose-derived stem cells showed low risk of tumourigenicity

Wan Kamarul Zaman, W. S., Makpol, S., Sathapan, S. & Chua, K. H. Jan 2014 In : Journal of Tissue Engineering and Regenerative Medicine. 8, 1, p. 67-76 10 p.

Research output: Contribution to journalArticle

Stem cells
Stem Cells
Cell culture
Telomerase
Telomere
3 Citations

New method for the isolation of endothelial cells from large vessels

Ataollahi, F., Pingguan-Murphy, B., Moradi, A., Bakar Wan Abas, W. A., Chua, K. H. & Abu Osman, N. A. 2014 In : Cytotherapy. 16, 8, p. 1145-1152 8 p.

Research output: Contribution to journalArticle

Endothelial Cells
Digestion
Research Personnel
von Willebrand Factor
Collagenases
10 Citations

Osteogenic potential of in situ TiO2 nanowire surfaces formed by thermal oxidation of titanium alloy substrate

Tan, A. W., Ismail, R., Chua, K. H., Ahmad, R., Akbar, S. A. & Pingguan-Murphy, B. 30 Nov 2014 In : Applied Surface Science. 320, p. 161-170 10 p.

Research output: Contribution to journalArticle

Titanium alloys
Control surfaces
Nanowires
Osteoblasts
Cell adhesion
2 Citations

Phenotypic characterization of culture expanded rabbit limbal corneal keratocytes

Abd Ghafar, N., Chua, K. H., Wan Ngah, W. Z., Che Hamzah, J., Othman, F., Abd Rahman, R. & Hj Idrus, R. 2014 In : Cell and Tissue Banking. 15, 1, p. 25-34 10 p.

Research output: Contribution to journalArticle

Corneal Keratocytes
Aldehyde Dehydrogenase
Keratin-3
Collagen Type I
Aldehydes
4 Citations

Proliferation and stemness preservation of human adipose-derived stem cells by surface-modified in situ TiO2 nanofibrous surfaces

Tan, A. W., Tay, L., Chua, K. H., Ahmad, R., Akbar, S. A. & Pingguan-Murphy, B. 21 Nov 2014 In : International Journal of Nanomedicine. 9, 1, p. 5389-5401 13 p.

Research output: Contribution to journalArticle

Stem cells
Stem Cells
Nanofibers
Electron Scanning Microscopy
Cell proliferation
6 Citations

Retropatellar fat pad-derived stem cells from older osteoarthritic patients have lesser differentiation capacity and expression of stemness genes

Chua, K. H., Zaman Wan Safwani, W. K., Hamid, A. A., Shuhup, S. K., Mohd Haflah, N. H. & Mohd Yahaya, N. H. 2014 In : Cytotherapy. 16, 5, p. 599-611 13 p.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Adipose Tissue
Stem Cells
Gene Expression
Cartilage
14 Citations

Role of rutin on nitric oxide synthesis in human umbilical vein endothelial cells

Ugusman, A., Zakaria, Z., Chua, K. H., Megat Mohd Nordin, N. A. & Abdullah Mahdy, Z. 2014 In : Scientific World Journal. 2014, 169370

Research output: Contribution to journalArticle

Rutin
Endothelial cells
Human Umbilical Vein Endothelial Cells
nitric oxide
Nitric Oxide
3 Citations

The use of autologous fibrin as a scaffold for cultivating autologous conjunctiva in the treatment of conjunctival defect

Safinaz, M. K., Norzana, A. G., Hairul Nizam, M. H., Ropilah, A. R., Faridah, H. A., Chua, K. H., Ruszymah, B. H. I. & Jemaima, C. H. 6 Nov 2014 In : Cell and Tissue Banking. 15, 4, p. 619-626 8 p.

Research output: Contribution to journalArticle

Conjunctiva
Fibrin
Scaffolds
Amnion
Membranes
6 Citations

Vitamin E: A potential therapy for gastric mucosal injury

Kamisah, Y., Qodriyah, H. M. S., Chua, K. H. & Nur Azlina, M. F. 1 Dec 2014 In : Pharmaceutical Biology. 52, 12, p. 1591-1597 7 p.

Research output: Contribution to journalArticle

Vitamin E
Stomach
Tocotrienols
Tocopherols
Wounds and Injuries
2013
9 Citations

Alteration of gene expression levels during osteogenic induction of human adipose derived stem cells in long-term culture

Safwani, W. K. Z. W., Makpol, S., Sathapan, S. & Chua, K. H. Jun 2013 In : Cell and Tissue Banking. 14, 2, p. 289-301 13 p.

Research output: Contribution to journalArticle

Stem cells
Cell culture
Gene expression
Stem Cells
Gene Expression
22 Citations

Edible Bird's nest extract as a chondro-protective agent for human chondrocytes isolated from osteoarthritic knee: In vitro study

Chua, K. H., Lee, T. H., Nagandran, K., Md Yahaya, N. H., Lee, C. T., Tjih, E. T. T. & Abdul Aziz, R. 22 Jan 2013 In : BMC Complementary and Alternative Medicine. 13, 19

Research output: Contribution to journalArticle

Protective Agents
Chondrocytes
Birds
Knee
Joints
4 Citations

Effects of keratinocyte growth factor on skin epithelial differentiation of human amnion epithelial cells

Fatimah, S. S., Tan, G. C., Chua, K., Tan, A. E., Nur Azurah, A. G. & Hayati, A. R. Aug 2013 In : Burns. 39, 5, p. 905-915 11 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 7
Amnion
Epithelial Cells
Skin
Gene Expression
12 Citations

Effects of serum reduction and VEGF supplementation on angiogenic potential of human adipose stromal cells in vitro

Chua, K. H., Raduan, F., Wan Safwani, W. K. Z., Manzor, N. F. M., Pingguan-Murphy, B. & Sathapan, S. Jun 2013 In : Cell Proliferation. 46, 3, p. 300-311 12 p.

Research output: Contribution to journalArticle

Stromal Cells
Vascular Endothelial Growth Factor A
Serum
Gene Expression
Real-Time Polymerase Chain Reaction
8 Citations
Fibroblasts
Microarray Analysis
Microarrays
Diploidy
Gene expression
3 Citations

Human forniceal region is the stem cell-rich zone of the conjunctival epithelium

Harun, M. H. N., Sepian, S. N., Chua, K. H., Ropilah, A. R., Abd Ghafar, N., Che-Hamzah, J., Bt Hj Idrus, R. & Annuar, F. H. Mar 2013 In : Human Cell. 26, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

Conjunctiva
Stem Cells
Epithelium
Pterygium
Genes
5 Citations

Organotypic culture of human amnion cells in air-liquid interface as a potential substitute for skin regeneration

Fatimah, S. S., Chua, K., Tan, G. C., Azmi, T. I., Tan, A. E. & Rahman, H. A. 2013 In : Cytotherapy. 15, 8, p. 1030-1041 12 p.

Research output: Contribution to journalArticle

Artificial Skin
Amnion
Regeneration
Air
Epithelial Cells
3 Citations

Pro-angiogenic potential of human chorion-derived stem cells: In vitro and in vivo evaluation

Fariha, M. M. N., Chua, K. H., Tan, G. C., Lim, Y. H. & Hayati, A. R. May 2013 In : Journal of Cellular and Molecular Medicine. 17, 5, p. 681-692 12 p.

Research output: Contribution to journalArticle

Chorion
Stem Cells
Blood Vessels
CD31 Antigens
In Vitro Techniques